SwePub
Sök i LIBRIS databas

  Utökad sökning

L773:1176 6328
 

Sökning: L773:1176 6328 > Factors associated ...

  • Jönsson, BengtStockholm School of Economics,Handelshögskolan i Stockholm (författare)

Factors associated with failure to achieve remission and with relapse after remission in patients with major depressive disorder in the PERFORM study

  • Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

  • Dove Medical Press,2017

Nummerbeteckningar

  • LIBRIS-ID:oai:hhs.se:1155070260006056
  • https://research.hhs.se/esploro/outputs/journalArticle/Factors-associated-with-failure-to-achieve/991001480593506056URI
  • https://doi.org/10.2147/NDT.S136343DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Background: The Prospective Epidemiological Research on Functioning Outcomes Related to Major Depressive Disorder (PERFORM) study has been initiated to better understand the course of a depressive episode and its impact on patient functioning. This analysis aimed to identify sociodemographic and clinical factors associated with failure to achieve remission at month 2 after initiating or switching antidepressant monotherapy and with subsequent relapse at month 6 for patients in remission at month 2. Materials and methods: This was a 2-year observational cohort study in 1,159 outpatients aged 18–65 years with major depressive disorder initiating or undergoing the first switch of antidepressant monotherapy. Factors with P8 weeks (OR 0.51), being in psychotherapy (OR 0.51), sexual dysfunction (OR 0.62), and severity of depression (OR 0.87). Factors significantly associated with relapse at month 6 were male sex (OR 2.47), being married or living as a couple (OR 2.73), residual patient-reported cognitive symptoms at 2 months (OR 1.12 per additional unit of Perceived Deficit Questionnaire-5 score) and residual depressive symptoms at 2 months (OR 1.27 per additional unit of Patient Health Questionnaire-9 score). Conclusion: Different factors appear to be associated with failure to achieve remission in patients with major depressive disorder and with subsequent relapse in patients who do achieve remission. Patient-reported cognitive dysfunction is an easily measurable and treatable characteristic that may be associated with an increased likelihood of relapse at 6 months in patients who have achieved remission.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Saragoussi, DelphineLundbeck SAS (författare)
  • Touya, MaëlysLundbeck Research USA (författare)
  • Haro, J. M.University of Barcelona (författare)
  • Knapp, Martin R.J.London School of Economics and Political Science (GB) (författare)
  • Botrel, BastienLundbeck SAS (författare)
  • Florea, IoanaLundbeck SAS (författare)
  • Loft, HenrikLundbeck SAS (författare)
  • Rive, BenoîtLundbeck SAS (författare)
  • Handelshögskolan i StockholmStockholm School of Economics (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Neuropsychiatric Disease and Treatment: Dove Medical Press13, s. 2151-21651176-6328

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy