Search: (WFRF:(Munoz Xavier)) pers:(Taddeo Frank J.) spr:eng
> (2008) >
HPV antibody levels...
HPV antibody levels and clinical efficacy following administration of a prophylactic quadrivalent HPV vaccine
- Article/chapterEnglish2008
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:00c798d7-5686-4a46-98dc-aee56f4db5cb
-
https://lup.lub.lu.se/record/1376300URI
-
https://doi.org/10.1016/j.vaccine.2008.09.073DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:118062132URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
The efficacy of the quadrivalent Human Papillomavirus (HPV) vaccine is thought to be mediated by humoral immunity. We evaluated the correlation between quadrivalent HPV vaccine-induced serum anti-HPV responses and efficacy. 17,622 women were vaccinated at day 1, and months 2 and 6. At day I and at 6-12 months intervals for up to 48 months, subjects underwent Papanicolaou and genital HPV testing. No immune correlate of protection could be found due to low number of cases. Although 40% of vaccine subjects were anti-HPV 18 seronegative at end-of-study, efficacy against HPV 18-related disease remained high (98.4%; 95% CI: 90.5-100.0) despite high attack rates in the placebo group. These results suggest vaccine-induced protection via immune memory, or lower than detectable HPV 18 antibody titers. (C) 2008 Elsevier Ltd. All rights reserved.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Kjaer, Susanne K.
(author)
-
Wheeler, Cosette M.
(author)
-
Sigurdsson, Kristjan
(author)
-
Iversene, Ole-Erik
(author)
-
Hernandez-Avila, Mauricio
(author)
-
Perez, Gonzalo
(author)
-
Brown, Darron R.
(author)
-
Koutsky, Laura A.
(author)
-
Tay, Eng Hseon
(author)
-
Garcia, Patricia
(author)
-
Ault, Kevin A.
(author)
-
Garland, Suzanne M.
(author)
-
Leodolter, Sepp
(author)
-
Olssonn, Sven-Eric
(author)
-
Tang, Grace W. K.
(author)
-
Ferris, Daron G.
(author)
-
Paavonen, Jorma
(author)
-
Lehtinen, Matti
(author)
-
Steben, Marc
(author)
-
Bosch, Xavier
(author)
-
Dillner, JoakimKarolinska Institutet,Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups(Swepub:lu)mikr-jdi
(author)
-
Kurmanv, Robert J.
(author)
-
Majewski, Slawomir
(author)
-
Munoz, Nubia
(author)
-
Myers, Evan R.
(author)
-
Villa, Luisa L.
(author)
-
Taddeo, Frank J.
(author)
-
Roberts, Christine
(author)
-
Tadesse, Amha
(author)
-
Bryan, Janine
(author)
-
Lupinaccia, Lisa C.
(author)
-
Giacoletti, Katherine E. D.
(author)
-
Lu, Shuang
(author)
-
Vuocolo, Scott
(author)
-
Hesley, Teresa M.
(author)
-
Haupt, Richard M.
(author)
-
Barr, Eliav
(author)
-
Klinisk mikrobiologi, MalmöForskargrupper vid Lunds universitet
(creator_code:org_t)
Related titles
-
In:Vaccine: Elsevier BV26:52, s. 6844-68511873-25180264-410X
Internet link
Find in a library
-
Vaccine
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Joura, Elmar A.
-
Kjaer, Susanne K ...
-
Wheeler, Cosette ...
-
Sigurdsson, Kris ...
-
Iversene, Ole-Er ...
-
Hernandez-Avila, ...
-
show more...
-
Perez, Gonzalo
-
Brown, Darron R.
-
Koutsky, Laura A ...
-
Tay, Eng Hseon
-
Garcia, Patricia
-
Ault, Kevin A.
-
Garland, Suzanne ...
-
Leodolter, Sepp
-
Olssonn, Sven-Er ...
-
Tang, Grace W. K ...
-
Ferris, Daron G.
-
Paavonen, Jorma
-
Lehtinen, Matti
-
Steben, Marc
-
Bosch, Xavier
-
Dillner, Joakim
-
Kurmanv, Robert ...
-
Majewski, Slawom ...
-
Munoz, Nubia
-
Myers, Evan R.
-
Villa, Luisa L.
-
Taddeo, Frank J.
-
Roberts, Christi ...
-
Tadesse, Amha
-
Bryan, Janine
-
Lupinaccia, Lisa ...
-
Giacoletti, Kath ...
-
Lu, Shuang
-
Vuocolo, Scott
-
Hesley, Teresa M ...
-
Haupt, Richard M ...
-
Barr, Eliav
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Microbiology in ...
- Articles in the publication
-
Vaccine
- By the university
-
Lund University
-
Karolinska Institutet