Search: WFRF:(Bjørnland Kristin) >
Management strategi...
Management strategies and treatment results of pediatric choledochal malformations in the Nordic countries
-
- Hukkinen, Maria (author)
- Helsinki University Children's Hospital
-
- Björnland, Kristin (author)
- Oslo university hospital
-
- Gatzinsky, Vladimir (author)
- Queen Silvia Children’s Hospital
-
show more...
-
- Iber, Tarja (author)
- Tampere University Hospital
-
- Johansen, Lars S. (author)
- Copenhagen University Hospital
-
- Qvist, Niels (author)
- Odense University Hospital
-
- Stenström, Pernilla (author)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Barnkirurgi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Pediatric surgery,Lund University Research Groups,Skåne University Hospital
-
- Svensson, Jan F (author)
- Karolinska Institutet
-
- Pakarinen, Mikko P. (author)
- Helsinki University Central Hospital
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2020
- 2020
- English 8 s.
-
In: HPB. - : Elsevier BV. - 1365-182X. ; 22:1, s. 161-168
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
http://www.hpbonline...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Background: Incidence and long-term outcomes of choledochal malformations (CMs) in children remain unclear. Methods: Clinical characteristics, operative details, complications, and follow-up data were collected from eight pediatric surgical centers in Sweden, Norway, Denmark, and Finland, which also answered a questionnaire addressing management practices. Results: During 2000–2017, 126 pediatric CMs were diagnosed, corresponding an incidence of 1:37,400. Diagnostic, treatment, and follow-up practices varied markedly. Of patients with complete clinical data (n = 119), 85% and 11% had type I and IV CMs and were managed by open hepaticojejunostomy at median age of 2.5 (interquartile range 0.46–5.8) years. Associated malformations were more common in fusiform and type IV (23%) than cystic CMs (8%, p = 0.043). Pancreaticobiliary maljunction was more frequently confirmed in patients presenting with pancreatitis (26% vs. 7%, p = 0.005) and with fusiform CMs (56% vs. 25%, p = 0.001). Cholangitis/pancreatitis episodes, occurring in 12% during postoperative follow-up of 4.0 (2.0–7.9) years, associated with longer surveillance (OR 1.32, 95% CI 1.13–1.54, p < 0.001). However, only two thirds of centers continued follow-up until adulthood. No malignancies were reported. Conclusions: CM incidence was higher than traditionally reported among Western populations. Although open hepaticojejunostomy carries good short-term outcomes, long-term morbidity is noteworthy. Standardized evidence-based management strategies and long-term follow-up are encouraged.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
-
HPB
(Search for host publication in LIBRIS)
To the university's database