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EULAR points to con...
EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis
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- Basu, Neil (author)
- University of Aberdeen, Aberdeen, UK
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- Watts, Richard (author)
- University of East Anglia, School of Medicine, Norwich, Norfolk, UK
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- Bajema, Ingeborg (author)
- Leiden University Medical Center, Leiden, The Netherlands
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- Baslund, Bo (author)
- Rigshospitalet, Copenhagen, Denmark
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- Bley, Thorsten (author)
- University Hospital Freiburg, Freiburg, Germany
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- Boers, Maarten (author)
- VU University Medical Center, Amsterdam, The Netherlands
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- Brogan, Paul (author)
- Institute of Child Health, London, UK
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- Calabrese, Len (author)
- Cleveland Clinic Foundation, Cleveland, Ohio, USA
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- Cid, Maria C. (author)
- Hospital Clinic, University of Barcelona IDIBAPS, Barcelona, Spain
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- Cohen-Tervaert, Jan Willem (author)
- Maastricht UMC, Maastricht, The Netherlands
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- Flores-Suarez, Luis Felipe (author)
- National Institute of Respiratory Disease, Mexico City, Mexico
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- Fujimoto, Shouichi (author)
- Miyazaki University, Miyazaki, Japan
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- de Groot, Kirsten (author)
- Klinikum Offenbach, Offenbach, Germany
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- Guillevin, Loic (author)
- University of Paris Descartes, Paris, France
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- Hatemi, Gulen (author)
- University of Istanbul, Istanbul, Turkey
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- Hauser, Thomas (author)
- Immunologie-Zentrum Zürich, Zurich, Switzerland
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- Jayne, David (author)
- Addenbrooke's Hospital, Cambridge, UK
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- Jennette, Charles (author)
- University of North Carolina, Chapel Hill, North Carolina, USA
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- Kallenberg, Cees G. M. (author)
- University Hospital Groningen, Groningen, The Netherlands
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- Kobayashi, Shigeto (author)
- Juntendo Koshigaya Hospital, Saitama, Japan
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- Little, Mark A. (author)
- Renal Institute of Birmingham, University of Birmingham, Birmingham, UK
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- Mahr, Alfred (author)
- University of Paris Descartes, Paris, France
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- McLaren, John (author)
- Whytemans Brae Hospital, Kirkcaldy, Fife, UK
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- Merkel, Peter A. (author)
- Boston University School of Medicine, Boston, Massachusetts, USA
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- Ozen, Seza (author)
- Hacettepe University, Ankara, Turkey
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- Puechal, Xavier (author)
- Centre Hospitalier Le Mans, Le Mans, France
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- Rasmussen, Niels (author)
- Rigshospitalet, Copenhagen, Denmark
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- Salama, Alan (author)
- Imperial College London, London, UK
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- Salvarani, Carlo (author)
- Arcispedale S Maria Nuova, Reggio Emilia, Italy
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- Savage, Caroline (author)
- Renal Institute of Birmingham, University of Birmingham, Birmingham, UK
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- Scott, David G. I. (author)
- Norfolk and Norwich University Hospital Trust, Norwich, Norfolk, UK
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- Segelmark, Mårten (author)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University, Lund, Sweden
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- Specks, Ulrich (author)
- Mayo Clinc, Minnesota, Minneapolis, USA
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- Sunderkoeetter, Cord (author)
- Universitätsklinikum Münster, Münich, Germany
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- Suzuki, Kazuo (author)
- Chiba University Graduate School of Medicine, Chiba, Japan
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- Tesar, Vladimir (author)
- Charles University, Prague, Czech Republic
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- Wiik, Allan (author)
- Statens Serum Institut, Copenhagen, Denmark
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- Yazici, Hasan (author)
- University of Istanbul, Istanbul, Turkey
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- Luqmani, Raashid (author)
- University of Oxford, Oxford, UK
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(creator_code:org_t)
- 2010-05-06
- 2010
- English.
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In: Annals of the Rheumatic Diseases. - London, UK : BMJ. - 1468-2060 .- 0003-4967. ; 69:10, s. 1744-1750
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Abstract
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- Objectives The systemic vasculitides are multiorgan diseases where early diagnosis and treatment can significantly improve outcomes. Robust nomenclature reduces diagnostic delay. However, key aspects of current nomenclature are widely perceived to be out of date, these include disease definitions, classification and diagnostic criteria. Therefore, the aim of the present work was to identify deficiencies and provide contemporary points to consider for the development of future definitions and criteria in systemic vasculitis. Methods The expert panel identified areas of concern within existing definitions/criteria. Consequently, a systematic literature review was undertaken looking to address these deficiencies and produce 'points to consider' in accordance with standardised European League Against Rheumatism (EULAR) operating procedures. In the absence of evidence, expert consensus was used. Results There was unanimous consensus for re-evaluating existing definitions and developing new criteria. A total of 17 points to consider were proposed, covering 6 main areas: biopsy, laboratory testing, diagnostic radiology, nosology, definitions and research agenda. Suggestions to improve and expand current definitions were described including the incorporation of anti-neutrophil cytoplasm antibody and aetiological factors, where known. The importance of biopsy in diagnosis and exclusion of mimics was highlighted, while equally emphasising its problems. Thus, the role of alternative diagnostic tools such as MRI, ultrasound and surrogate markers were also discussed. Finally, structures to develop future criteria were considered. Conclusions Limitations in current classification criteria and definitions for vasculitis have been identified and suggestions provided for improvement. Additionally it is proposed that, in combination with the updated evidence, these should form the basis of future attempts to develop and validate revised criteria and definitions of vasculitis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Basu, Neil
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Watts, Richard
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Bajema, Ingeborg
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Baslund, Bo
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Bley, Thorsten
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Boers, Maarten
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show more...
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Brogan, Paul
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Calabrese, Len
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Cid, Maria C.
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Cohen-Tervaert, ...
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Flores-Suarez, L ...
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Fujimoto, Shouic ...
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de Groot, Kirste ...
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Guillevin, Loic
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Hatemi, Gulen
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Hauser, Thomas
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Jayne, David
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Jennette, Charle ...
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Kallenberg, Cees ...
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Kobayashi, Shige ...
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Little, Mark A.
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Mahr, Alfred
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McLaren, John
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Merkel, Peter A.
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Ozen, Seza
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Puechal, Xavier
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Rasmussen, Niels
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Salama, Alan
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Salvarani, Carlo
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Savage, Caroline
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Scott, David G. ...
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Segelmark, Mårte ...
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Specks, Ulrich
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Sunderkoeetter, ...
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Suzuki, Kazuo
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Tesar, Vladimir
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Wiik, Allan
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Yazici, Hasan
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Luqmani, Raashid
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Rheumatology and ...
- Articles in the publication
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Annals of the Rh ...
- By the university
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Lund University
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Linköping University