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The epidemic of met...
The epidemic of methylisothiazolinone : A European prospective study
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- Schwensen, Jakob F. (författare)
- University of Copenhagen
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- Uter, Wolfgang (författare)
- Friedrich-Alexander University Erlangen-Nürnberg
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- Bruze, Magnus (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Svedman, Cecilia (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Goossens, An (författare)
- University Hospitals Leuven
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- Wilkinson, Mark (författare)
- Leeds Teaching Hospitals NHS Trust
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- Giménez Arnau, Ana (författare)
- Autonomous University of Barcelona
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- Gonçalo, Margarida (författare)
- University of Coimbra
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- Andersen, Klaus E. (författare)
- University of Southern Denmark
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- Paulsen, Evy (författare)
- University of Southern Denmark
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- Agner, Tove (författare)
- Bispebjerg Hospital
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- Foti, Caterina (författare)
- University of Bari Aldo Moro
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- Aalto-Korte, Kristiina (författare)
- Finnish Institute of Occupational Health
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- Mcfadden, John (författare)
- St John's Institute of Dermatology
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- White, Ian (författare)
- St John's Institute of Dermatology
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- Johansen, Jeanne D. (författare)
- University of Copenhagen
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(creator_code:org_t)
- 2016-12-28
- 2017
- Engelska.
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873. ; 76:5, s. 272-279
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: The use of methylisothiazolinone (MI) in cosmetic products has caused an unprecedented epidemic of MI contact allergy. Current data concerning exposures at a European level are required. Objectives: To describe demographics and MI exposures for European patients with MI contact allergy. Methods: Eleven European dermatology departments from eight European countries prospectively collected data between 1 May and 31 October 2015 among consecutive patients who had positive patch test reactions to MI (2000ppm aq.). Results: A total of 6.0% (205/3434; range 2.6-13.0%) of patients had positive patch test reactions to MI. Dermatitis most frequently affected the hands (43.4%), face (32.7%), arms (14.6%), and eyelids (11.7%); 12.7% had widespread dermatitis. For 72.7% (149/205), MI contact allergy was currently relevant mainly because of exposure to cosmetic products (83.2%; 124/149). Of these 124 patients, 19.5% were exposed to leave-on and rinse-off cosmetic products, 24.8% only to leave-on cosmetic products and 38.9% only to rinse-off cosmetic products containing MI or methylchloroisothiazolinone/MI. The majority of these (79%) noted onset of their dermatitis between 2013 and 2015. Fifteen patients (7.3%) had previously experienced allergic reactions when they were in newly painted rooms. Conclusion: Clinically relevant MI contact allergy remains prevalent across European countries, mainly because of exposure to rinse-off and leave-on cosmetic products.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- Allergic contact dermatitis
- CAS no. 2682-20-4
- Cosmetics
- Exposure
- Methylchloroisothiazolinone
- Methylisothiazolinone
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Schwensen, Jakob ...
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Uter, Wolfgang
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Bruze, Magnus
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Svedman, Cecilia
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Goossens, An
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Wilkinson, Mark
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Giménez Arnau, A ...
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Gonçalo, Margari ...
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Andersen, Klaus ...
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Paulsen, Evy
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Agner, Tove
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Foti, Caterina
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Aalto-Korte, Kri ...
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Mcfadden, John
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White, Ian
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Johansen, Jeanne ...
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