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Rituximab in adult ...
Rituximab in adult minimal change disease and focal segmental glomerulosclerosis - What is known and what is still unknown?
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- Gauckler, Philipp (författare)
- Medical University of Innsbruck,Med Univ Innsbruck, Austria
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- Shin, Jae Il (författare)
- Yonsei University,Severance Hospital,Yonsei Univ, South Korea; Severance Childrens Hosp, South Korea; Yonsei Univ, South Korea
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- Alberici, Federico (författare)
- University of Brescia,Spedali Civili Di Brescia,ASST Spedali Civili Brescia, Italy; Univ Brescia, Italy
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- Audard, Vincent (författare)
- University of Paris-Est,Paris East Univ, France
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- Bruchfeld, Annette (författare)
- Karolinska Institutet,Linköpings universitet,Linköping University,Karolinska University Hospital,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Karolinska Univ Hosp, Sweden
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- Busch, Martin (författare)
- Universitätsklinikum Jena,Friedrich Schiller Univ, Germany
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- Cheung, Chee Kay (författare)
- University of Leicester,University Hospitals of Leicester NHS Trust,Univ Leicester, England; Univ Hosp Leicester NHS Trust, England
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- Crnogorac, Matija (författare)
- Dubrava University Hospital,Dubrava Univ Hosp, Croatia
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- Delbarba, Elisa (författare)
- University of Brescia,Univ Brescia, Italy
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- Eller, Kathrin (författare)
- Medical University of Graz,Med Univ Graz, Austria
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- Faguer, Stanislas (författare)
- Institute of Cardiovascular and Metabolic Diseases (I2MC),Toulouse University Hospital,Ctr Hosp Univ Toulouse, France; Inst Natl Sante & Rech Med, France
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- Galesic, Kresimir (författare)
- Dubrava University Hospital,Dubrava Univ Hosp, Croatia
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- Griffin, Siân (författare)
- University Hospital of Wales,Univ Hosp Wales, Wales
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- Hrušková, Zdenka (författare)
- General University Hospital in Prague,Charles University in Prague,Charles Univ Prague, Czech Republic; Gen Univ Hosp, Czech Republic
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- Jeyabalan, Anushya (författare)
- Columbia University,Columbia Univ, NY USA
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- Karras, Alexandre (författare)
- Assistance Publique des Hôpitaux de Paris,Hop Europeen Georges Pompidou, France
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- King, Catherine (författare)
- University of Birmingham,Univ Birmingham, England
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- Kohli, Harbir Singh (författare)
- Postgraduate Institute of Medical Education and Research,Post Grad Inst Med Educ & Res, India
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- Maas, Rutger (författare)
- Radboud University Medical Center,Radboud Univ Nijmegen, Netherlands
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- Mayer, Gert (författare)
- Medical University of Innsbruck,Med Univ Innsbruck, Austria
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- Moiseev, Sergey (författare)
- I.M. Sechenov First Moscow State Medical University,Sechenov First Moscow State Med Univ, Russia
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- Muto, Masahiro (författare)
- Juntendo University,Juntendo Univ, Japan
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- Odler, Balazs (författare)
- Medical University of Graz,Med Univ Graz, Austria
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- Pepper, Ruth J. (författare)
- University College London,UCL, England
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- Quintana, Luis F. (författare)
- University of Barcelona,Univ Barcelona, Spain
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- Radhakrishnan, Jai (författare)
- Columbia University,Columbia Univ, NY USA
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- Ramachandran, Raja (författare)
- Postgraduate Institute of Medical Education and Research,Post Grad Inst Med Educ & Res, India
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- Salama, Alan D. (författare)
- University College London,UCL, England
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- Segelmark, Mårten (författare)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Skane Univ Hosp, Sweden
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- Tesař, Vladimír (författare)
- Charles University in Prague,General University Hospital in Prague,Charles Univ Prague, Czech Republic; Gen Univ Hosp, Czech Republic
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- Wetzels, Jack (författare)
- Radboud University Medical Center,Radboud Univ Nijmegen, Netherlands
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- Willcocks, Lisa (författare)
- Addenbrooke's Hospital,Cambridge Univ Hosp, England
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- Windpessl, Martin (författare)
- Klinikum Wels Grieskirchen, Austria; Johannes Kepler Univ Linz, Austria,Johannes-Kepler-University of Linz
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- Zand, Ladan (författare)
- Mayo Clinic Minnesota,Mayo Clin, MN USA
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- Zonozi, Reza (författare)
- Massachusetts General Hospital,Massachusetts Gen Hosp, MA 02114 USA
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- Kronbichler, Andreas (författare)
- Medical University of Innsbruck,Med Univ Innsbruck, Austria
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(creator_code:org_t)
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- Elsevier BV, 2020
- 2020
- Engelska.
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Ingår i: Autoimmunity Reviews. - : Elsevier BV. - 1568-9972 .- 1873-0183. ; 19:11
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://doi.org/10.1...
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https://liu.diva-por... (primary) (Raw object)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Primary forms of minimal change disease and focal segmental glomerulosclerosis are rare podocytopathies and clinically characterized by nephrotic syndrome. Glucocorticoids are the cornerstone of the initial immunosuppressive treatment in these two entities. Especially among adults with minimal change disease or focal segmental glomerulosclerosis, relapses, steroid dependence or resistance are common and necessitate re-initiation of steroids and other immunosuppressants. Effective steroid-sparing therapies and introduction of less toxic immunosuppressive agents are urgently needed to reduce undesirable side effects, in particular for patients whose disease course is complex. Rituximab, a B cell depleting monoclonal antibody, is increasingly used off-label in these circumstances, despite a low level of evidence for adult patients. Hence, critical questions concerning drug-safety, long-term efficacy and the optimal regimen for rituximab-treatment remain unanswered. Evidence in the form of large, multicenter studies and randomized controlled trials are urgently needed to overcome these limitations.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- Focal segmental glomerulosclerosis
- Infections
- Long-term remission
- Minimal change disease
- Nephrotic syndrome
- Rituximab
- Nephrotic syndrome; Rituximab; Minimal change disease; Focal segmental glomerulosclerosis; Long-term remission; Infections
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Till lärosätets databas
- Av författaren/redakt...
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Gauckler, Philip ...
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Shin, Jae Il
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Alberici, Federi ...
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Audard, Vincent
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Bruchfeld, Annet ...
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Busch, Martin
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visa fler...
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Cheung, Chee Kay
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Crnogorac, Matij ...
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Delbarba, Elisa
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Eller, Kathrin
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Faguer, Stanisla ...
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Galesic, Kresimi ...
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Griffin, Siân
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Hrušková, Zdenka
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Jeyabalan, Anush ...
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Karras, Alexandr ...
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King, Catherine
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Kohli, Harbir Si ...
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Maas, Rutger
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Mayer, Gert
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Moiseev, Sergey
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Muto, Masahiro
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Odler, Balazs
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Pepper, Ruth J.
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Quintana, Luis F ...
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Radhakrishnan, J ...
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Ramachandran, Ra ...
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Salama, Alan D.
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Segelmark, Mårte ...
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Tesař, Vladimír
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Wetzels, Jack
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Willcocks, Lisa
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Windpessl, Marti ...
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Zand, Ladan
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Zonozi, Reza
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Kronbichler, And ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Urologi och njur ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Reumatologi och ...
- Artiklar i publikationen
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Autoimmunity Rev ...
- Av lärosätet
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Lunds universitet
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Linköpings universitet
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Karolinska Institutet