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Evaluation of the m...
Evaluation of the measurement properties of symptom measurement instruments for atopic eczema : A systematic review
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- Gerbens, L. A A (author)
- Academic Medical Center of University of Amsterdam (AMC)
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- Prinsen, C. A C (author)
- Amsterdam UMC - Vrije Universiteit Amsterdam
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- Chalmers, J. R. (author)
- University of Nottingham
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- Drucker, A. M. (author)
- Brown University
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- von Kobyletzki, L. B. (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups
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- Limpens, J. (author)
- Academic Medical Center of University of Amsterdam (AMC)
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- Nankervis, H. (author)
- University of Nottingham
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- Svensson, Åke (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups
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- Terwee, C. B. (author)
- Amsterdam UMC - Vrije Universiteit Amsterdam
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- Zhang, J. (author)
- Peking University
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- Apfelbacher, C. J. (author)
- University of Regensburg
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- Spuls, P. I. (author)
- Academic Medical Center of University of Amsterdam (AMC)
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(creator_code:org_t)
- 2016-07-13
- 2017
- English.
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In: Allergy: European Journal of Allergy and Clinical Immunology. - : Wiley. - 0105-4538. ; 72:1, s. 146-163
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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Abstract
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- Background: Symptoms have been identified as a core outcome domain for atopic eczema (AE) trials. Various instruments exist to measure symptoms in AE, but they vary in quality and there is a lack of standardization between clinical trials. Our objective was to systematically evaluate the quality of the evidence on the measurement properties of AE symptom instruments, thereby informing consensus discussions within the Harmonising Outcome Measures for Eczema (HOME) initiative regarding the most appropriate instruments for the core outcome domain symptoms. Methods: Using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist and predefined criteria for good measurement properties on identified development and validation studies of AE symptom instruments, a best evidence synthesis was performed to draw an overall conclusion on quality of the instruments and to provide recommendations. Results: Eighteen instruments were identified and evaluated. When the quality and results of the studies were considered, only five of these instruments had sufficient validation data to consider them for the core outcome set for the core outcome domain symptoms. These were the paediatric Itch Severity Scale (ISS), Patient-Oriented Eczema Measure (POEM), Patient-Oriented SCOring Atopic Dermatitis (PO-SCORAD), Self-Administered Eczema Area and Severity Index (SA-EASI) and adapted SA-EASI. Conclusions: ISS (paediatric version), POEM, PO-SCORAD, SA-EASI and adapted SA-EASI are currently the most appropriate instruments and therefore have the potential to be recommended as core symptom instrument in future clinical trials. These findings will be utilized for the development of a core outcome set for AE.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Keyword
- Atopic eczema
- Core outcome set
- Harmonising Outcome Measures for Eczema (HOME) initiative
- Measurement properties
- Symptoms
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Gerbens, L. A A
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Prinsen, C. A C
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Chalmers, J. R.
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Drucker, A. M.
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von Kobyletzki, ...
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Limpens, J.
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show more...
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Nankervis, H.
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Svensson, Åke
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Terwee, C. B.
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Zhang, J.
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Apfelbacher, C. ...
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Spuls, P. I.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dermatology and ...
- Articles in the publication
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Allergy: Europea ...
- By the university
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Lund University