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Search: id:"swepub:oai:lup.lub.lu.se:1537189e-911d-4ecf-a99b-5621a9ae1af9" > Risk factors for de...

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  • Mogard, E.Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital (author)

Risk factors for development and persistence of chronic widespread pain in spondyloarthritis : a population-based two-year follow-up study

  • Article/chapterEnglish2019

Publisher, publication year, extent ...

  • 2019-06-27
  • Informa UK Limited,2019

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  • LIBRIS-ID:oai:lup.lub.lu.se:1537189e-911d-4ecf-a99b-5621a9ae1af9
  • https://lup.lub.lu.se/record/1537189e-911d-4ecf-a99b-5621a9ae1af9URI
  • https://doi.org/10.1080/03009742.2019.1602163DOI
  • https://gup.ub.gu.se/publication/284996URI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype

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  • Objective: To study chronic widespread pain (CWP) over time in patients with spondyloarthritis (SpA), and to identify risk factors for development and persistence of CWP. Methods: In this cohort study with baseline and 2.5 year follow-up postal surveys, patients with ankylosing spondylitis (AS) and undifferentiated spondyloarthritis (USpA) (47% women) answered questions regarding pain, and were categorized as no chronic pain (NCP), chronic regional pain (CRP), or CWP. For each risk factor candidate (disease duration, body mass index, smoking, and patient-reported outcome measures), logistic regression analyses with CWP as the main outcome were performed separately, together with a basic model including age, gender, and SpA subgroup. Results: Altogether, 644 patients could be categorized at both time-points, yielding similar prevalence estimates at baseline and follow-up, although 38% transitioned between pain groups. Risk factors (odds ratio; 95% confidence interval) for development of CWP included more pain regions (1.36; 1.20‒1.53), higher pain intensity (1.35; 1.20‒1.52), worse fatigue (1.25; 1.13‒1.38), and worse global health (1.35; 1.19‒1.54). Persistent CWP was reported by 72%. In addition to factors predicting development of CWP, higher age (1.02; 1.00‒1.04), female gender (1.82; 1.06‒3.10), and anxiety (1.07; 1.00–1.14) also predicted persistence. Conclusion: The prevalence of CWP remained high over time, but with individual transitions between the pain groups. The development and persistence of CWP were predicted by more pain and worse health, with the addition of female gender and higher age for persistent CWP. Special attention and treatment alternatives for patients with SpA and concomitant CWP are essential in the clinic.

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  • Lindqvist, E.Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund Arthritis Research Group (LARG),Forskargrupper vid Lunds universitet,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Skåne University Hospital(Swepub:lu)reum-eli (author)
  • Bremander, A.Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Odense University Hospital,Spenshult Research and Development Center,University of Southern Denmark(Swepub:lu)med-aba (author)
  • Bergman, S.Gothenburg University,Göteborgs universitet,Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Sahlgrenska Academy,Spenshult Research and Development Center,Institutionen för medicin,Institute of Medicine(Swepub:gu)xberst (author)
  • Reumatologi och molekylär skelettbiologiSektion III (creator_code:org_t)

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  • In:Scandinavian Journal of Rheumatology: Informa UK Limited48:6, s. 460-4680300-97421502-7732

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By the author/editor
Mogard, E.
Lindqvist, E.
Bremander, A.
Bergman, S.
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and General Practice
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Rheumatology and ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Health Sciences
and Physiotherapy
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Scandinavian Jou ...
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Lund University
University of Gothenburg

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