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Lifestyle factors a...
Lifestyle factors and mortality risk in individuals with diabetes mellitus: are the associations different from those in individuals without diabetes?
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Sluik, Diewertje (author)
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Boeing, Heiner (author)
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Li, Kuanrong (author)
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Kaaks, Rudolf (author)
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Johnsen, Nina Fons (author)
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Tjonneland, Anne (author)
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Arriola, Larraitz (author)
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Barricarte, Aurelio (author)
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Masala, Giovanna (author)
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Grioni, Sara (author)
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Tumino, Rosario (author)
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Ricceri, Fulvio (author)
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Mattiello, Amalia (author)
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Spijkerman, Annemieke M. W. (author)
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van der A, Daphne L. (author)
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Sluijs, Ivonne (author)
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- Franks, Paul (author)
- Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups
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- Nilsson, Peter (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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- Orho-Melander, Marju (author)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups
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- Fhärm, Eva (author)
- Umeå universitet,Allmänmedicin
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- Rolandsson, Olov (author)
- Umeå universitet,Allmänmedicin
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Riboli, Elio (author)
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Romaguera, Dora (author)
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- Weiderpass, Elisabete (author)
- Karolinska Institutet
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Sanchez-Cantalejo, Emilio (author)
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Noethlings, Ute (author)
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(creator_code:org_t)
- 2013-10-17
- 2014
- English.
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In: Diabetologia. - : Springer Science and Business Media LLC. - 1432-0428 .- 0012-186X. ; 57:1, s. 63-72
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Abstract
Subject headings
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- Aims/hypothesis Thus far, it is unclear whether lifestyle recommendations for people with diabetes should be different from those for the general public. We investigated whether the associations between lifestyle factors and mortality risk differ between individuals with and without diabetes. Methods Within the European Prospective Investigation into Cancer and Nutrition (EPIC), a cohort was formed of 6,384 persons with diabetes and 258,911 EPIC participants without known diabetes. Joint Cox proportional hazard regression models of people with and without diabetes were built for the following lifestyle factors in relation to overall mortality risk: BMI, waist/height ratio, 26 food groups, alcohol consumption, leisure-time physical activity, smoking. Likelihood ratio tests for heterogeneity assessed statistical differences in regression coefficients. Results Multivariable adjusted mortality risk among individuals with diabetes compared with those without was increased, with an HR of 1.62 (95% CI 1.51, 1.75). Intake of fruit, legumes, nuts, seeds, pasta, poultry and vegetable oil was related to a lower mortality risk, and intake of butter and margarine was related to an increased mortality risk. These associations were significantly different in magnitude from those in diabetes-free individuals, but directions were similar. No differences between people with and without diabetes were detected for the other lifestyle factors. Conclusions/interpretation Diabetes status did not substantially influence the associations between lifestyle and mortality risk. People with diabetes may benefit more from a healthy diet, but the directions of association were similar. Thus, our study suggests that lifestyle advice with respect to mortality for patients with diabetes should not differ from recommendations for the general population.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Adiposity
- Alcohol
- Diabetes
- Lifestyle
- Mortality
- Nutrition
- Physical
- activity
- Smoking
- Adiposity
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Sluik, Diewertje
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Boeing, Heiner
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Li, Kuanrong
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Kaaks, Rudolf
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Johnsen, Nina Fo ...
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Tjonneland, Anne
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show more...
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Arriola, Larrait ...
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Barricarte, Aure ...
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Masala, Giovanna
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Grioni, Sara
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Tumino, Rosario
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Ricceri, Fulvio
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Mattiello, Amali ...
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Spijkerman, Anne ...
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van der A, Daphn ...
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Sluijs, Ivonne
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Franks, Paul
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Nilsson, Peter
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Orho-Melander, M ...
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Fhärm, Eva
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Rolandsson, Olov
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Riboli, Elio
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Romaguera, Dora
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Weiderpass, Elis ...
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Sanchez-Cantalej ...
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Noethlings, Ute
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
- Articles in the publication
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Diabetologia
- By the university
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Lund University
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Karolinska Institutet
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Umeå University