Search: id:"swepub:oai:lup.lub.lu.se:18771432-0c7f-4775-b871-e8e2d65cb7c5" >
MoonFit, a minimal ...
-
Robert, Philippe A.Helmholtz Centre for Infection Research
(author)
MoonFit, a minimal interface for fitting ODE dynamical models, bridging simulation by experimentalists and customization by C++ programmers
Publisher, publication year, extent ...
-
Cold Spring Harbor Laboratory,2018
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:18771432-0c7f-4775-b871-e8e2d65cb7c5
-
https://lup.lub.lu.se/record/18771432-0c7f-4775-b871-e8e2d65cb7c5URI
-
https://doi.org/10.1101/281188DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ovr swepub-publicationtype
-
Subject category:vet swepub-contenttype
Notes
-
The modelling of biological systems often consists into differential equation models that need to be fitted to experimental data. During this complex process, the practical experience of the biologist and the theoretical abstraction of the modeller require back-and-forth refinements of the model, design of new experiments and inclusion of more data-points into the fitting procedure. Available optimization interfaces rarely simultaneously allow customizations by the programmer and the capacity for the biologist to perform simulations or optimizations with a simple interface.Here, we provide the C++ code of a graphical user interface based on a user defined minimal C++ ODE model class. The graphical interface allows to perform simulations and optimizations without any knowledge in programming. The code was designed minimal and modular to be easily modified, with maximal freedom to link customized optimization libraries, solver or hand-made scripts. Moonfit is powerful enough to fit and compare models with high dimensionality, multiple datasets, to automatize optimizations, and to perform iterative fittings using data interpolation. We believe this will ease the interaction between modellers and experimental partners.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Jönsson, HenrikLund University,Lunds universitet,Beräkningsbiologi och biologisk fysik - Genomgår omorganisation,Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation,Naturvetenskapliga fakulteten,Computational Biology and Biological Physics - Undergoing reorganization,Department of Astronomy and Theoretical Physics - Undergoing reorganization,Faculty of Science,University of Cambridge(Swepub:lu)thep-hjo
(author)
-
Meyer-Hermann, MichaelTechnical University of Braunschweig,Helmholtz Centre for Infection Research
(author)
-
Helmholtz Centre for Infection ResearchBeräkningsbiologi och biologisk fysik - Genomgår omorganisation
(creator_code:org_t)
Related titles
-
In:bioRxiv: Cold Spring Harbor Laboratory
Internet link
To the university's database