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Insulin-like growth...
Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: results from the EPIC cohort
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Ose, J. (author)
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Fortner, R. T. (author)
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Schock, H. (author)
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Peeters, P. H. (author)
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Onland-Moret, N. C. (author)
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Bueno-de-Mesquita, H. B. (author)
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- Weiderpass, E. (author)
- Karolinska Institutet
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Gram, I. T. (author)
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Overvad, K. (author)
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Tjonneland, A. (author)
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Dossus, L. (author)
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Fournier, A. (author)
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Baglietto, L. (author)
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Trichopoulou, A. (author)
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Benetou, V. (author)
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Trichopoulos, D. (author)
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Boeing, H. (author)
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Masala, G. (author)
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Krogh, V. (author)
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Matiello, A. (author)
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Tumino, R. (author)
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Popovic, M. (author)
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Obon-Santacana, M. (author)
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Larranaga, N. (author)
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Ardanaz, E. (author)
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Sanchez, M-J (author)
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Menendez, V. (author)
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Chirlaque, M-D (author)
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Travis, R. C. (author)
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Khaw, K-T (author)
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- Brändstedt, Jenny (author)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Idahl, Annika (author)
- Umeå universitet,Obstetrik och gynekologi
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- Lundin, Eva (author)
- Umeå universitet,Patologi
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Rinaldi, S. (author)
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Kuhn, E. (author)
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Romieu, I. (author)
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Gunter, M. J. (author)
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Merritt, M. A. (author)
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Riboli, E. (author)
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Kaaks, R. (author)
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(creator_code:org_t)
- 2014-11-04
- 2015
- English.
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In: British Journal of Cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 112:1, s. 162-166
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http://dx.doi.org/10...
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Abstract
Subject headings
Close
- Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics. Methods: We conducted a nested case-control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics (n = 565 cases). Multivariable conditional logistic regression models were used to estimate associations. Results: We observed no association between IGF-I and EOC overall or by tumour characteristics. Conclusions: In the largest prospective study to date was no association between IGF-I and EOC risk. Pre-diagnostic serum IGF-I concentrations may not influence EOC risk.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- IGF-I
- ovarian cancer
- histological subtypes
- carcinogenesis
- type
- I/type II
- dualistic pathway
- IGF-I
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Ose, J.
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Fortner, R. T.
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Schock, H.
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Peeters, P. H.
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Onland-Moret, N. ...
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Bueno-de-Mesquit ...
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show more...
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Weiderpass, E.
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Gram, I. T.
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Overvad, K.
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Tjonneland, A.
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Dossus, L.
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Fournier, A.
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Baglietto, L.
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Trichopoulou, A.
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Benetou, V.
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Trichopoulos, D.
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Boeing, H.
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Masala, G.
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Krogh, V.
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Matiello, A.
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Tumino, R.
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Popovic, M.
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Obon-Santacana, ...
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Larranaga, N.
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Ardanaz, E.
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Sanchez, M-J
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Menendez, V.
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Chirlaque, M-D
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Travis, R. C.
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Khaw, K-T
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Brändstedt, Jenn ...
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Idahl, Annika
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Lundin, Eva
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Rinaldi, S.
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Kuhn, E.
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Romieu, I.
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Gunter, M. J.
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Merritt, M. A.
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Riboli, E.
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Kaaks, R.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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British Journal ...
- By the university
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Lund University
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Umeå University
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Karolinska Institutet