Substance Use, Hospitalizations, and Co-Occurring Disorders among Patients Transferred from a Needle Exchange Program to Opioid Maintenance Treatment

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Bråbäck, MartinLund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Enheten för klinisk beroendeforskning,Forskargrupper vid Lunds universitet,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical addiction research unit,Lund University Research Groups (author)

Substance Use, Hospitalizations, and Co-Occurring Disorders among Patients Transferred from a Needle Exchange Program to Opioid Maintenance Treatment

Article/chapterEnglish2022

Publisher, publication year, extent ...

2022-01-08
MDPI AG,2022

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LIBRIS-ID:oai:lup.lub.lu.se:1d27b903-33e8-4c8b-8287-d3a6a2e4a350
https://lup.lub.lu.se/record/1d27b903-33e8-4c8b-8287-d3a6a2e4a350URI
https://doi.org/10.3390/ijerph19020697DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:148657677URI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:art swepub-publicationtype
Subject category:ref swepub-contenttype

Notes

Opioid use disorders (OUD) is a relapsing condition with high mortality. Opioid maintenance treatment (OMT) reduces heroin use, and overall morbidity and mortality. The prevalence of psychiatric and substance use disorders, potential baseline predictors for psychiatric hospitalization, and psychiatric diagnoses at follow-up were investigated and may give hints about possible preventative strategies. The medical records for 71 patients were reviewed 36 months following referral to OMT from a needle exchange program (NEP). Their psychiatric diagnoses and hospitalizations were identified. Their baseline characteristics were assessed for potential differences between hospitalized versus non-hospitalized patients and between patients with and without psychiatric diagnoses in a longitudinal observational study without controls. A regression analysis was performed to identify predictors for hospitalization when controlling for OMT status. Sixty-five percent of the patients were hospitalized at least once with a psychiatric diagnosis. Substance-related reasons were prevalent, and detoxification occurred among 59% of patients, with sedative-hypnotics (benzodiazepines, zopiclone, zolpidem, and pregabalin) being the substance used by 52% of patients. Baseline use of these drugs and/or buprenorphine predicted for hospitalization when controlling for OMT status. During the follow-up period, 72% of patients met the criteria for a psychiatric diagnosis other than OUD. The prevalence of non-substance use disorders overlapping with SUD was 41%, and that overlapping with anxiety disorder was 27% of all participants. Increased attention to psychiatric co-occurring disorders in the treatment of OUD is required and the importance of addressing sedative-hypnotics use when initiating OMT is highlighted.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Psykiatri hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Psychiatry hsv//eng
Opioid maintenance treatment
Polysubstance use
Psychiatric co-occurring disorders
Psychiatric hospitalization

Added entries (persons, corporate bodies, meetings, titles ...)

Brantefors, AnnaSkåne University Hospital (author)
Franck, JohanKarolinska Institutet,Karolinska Institute (author)
Brådvik, LouiseLund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Enheten för klinisk beroendeforskning,Forskargrupper vid Lunds universitet,Lundbystudien,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical addiction research unit,Lund University Research Groups,The Lundby Study(Swepub:lu)med-lbd (author)
Isendahl, PernillaLund University,Lunds universitet,Kliniskt Centrum för Hälsofrämjande Vård,Forskargrupper vid Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Institutionen för kliniska vetenskaper, Malmö,Clinical Health Promotion Centre,Lund University Research Groups,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Sciences, Malmö,Skåne University Hospital(Swepub:lu)ark3-pis (author)
Nilsson, SuzanLund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-szn (author)
Troberg, KatjaLund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Enheten för klinisk beroendeforskning,Forskargrupper vid Lunds universitet,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical addiction research unit,Lund University Research Groups(Swepub:lu)med-kjt (author)
Håkansson, AndersLund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Enheten för klinisk beroendeforskning,Forskargrupper vid Lunds universitet,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical addiction research unit,Lund University Research Groups(Swepub:lu)med-adh (author)
Psykiatri, LundSektion IV (creator_code:org_t)

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In:International Journal of Environmental Research and Public Health: MDPI AG19:21661-78271660-4601

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By the author/editor: Bråbäck, Martin; Brantefors, Anna; Franck, Johan; Brådvik, Louise; Isendahl, Pernil ...; Nilsson, Suzan; show more...; Troberg, Katja; Håkansson, Ander ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

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