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Search: WFRF:(Ramsey Goldman Rosalind) > (2010-2014) > Non-Lymphoma Hemato...

  • Lu, Mary (author)

Non-Lymphoma Hematological Malignancies in Systemic Lupus Erythematosus

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • 2013-10-02
  • S. Karger AG,2013

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:1d2d69dd-2ce7-4bba-b4ef-1604476f8231
  • https://lup.lub.lu.se/record/4204162URI
  • https://doi.org/10.1159/000350165DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Objective: To describe non-lymphoma hematological malignancies in systemic lupus erythematosus (SLE). Methods: A large SLE cohort was linked to cancer registries. We examined the types of non-lymphoma hematological cancers. Results: In 16,409 patients, 115 hematological cancers [including myelodysplastic syndrome (MDS)] occurred. Among these, 33 were non-lymphoma. Of the 33 non-lymphoma cases, 13 were of lymphoid lineage: multiple myeloma (n = 5), plasmacytoma (n = 3), B cell chronic lymphocytic leukemia (B-CLL; n = 3), precursor cell lymphoblastic leukemia (n = 1) and unspecified lymphoid leukemia (n = 1). The remaining 20 cases were of myeloid lineage: MDS (n = 7), acute myeloid leukemia (AML; n = 7), chronic myeloid leukemia (CML; n = 2) and 4 unspecified leukemias. Most of these malignancies occurred in female Caucasians, except for plasma cell neoplasms (4/5 multiple myeloma and 1/3 plasmacytoma cases occurred in blacks). Conclusions: In this large SLE cohort, the most common non-lymphoma hematological malignancies were myeloid types (MDS and AML). This is in contrast to the general population, where lymphoid types are 1.7 times more common than myeloid non-lymphoma hematological malignancies. Most (80%) multiple myeloma cases occurred in blacks; this requires further investigation. (C) 2013 S. Karger AG, Basel

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Bernatsky, Sasha (author)
  • Ramsey-Goldman, Rosalind (author)
  • Petri, Michelle (author)
  • Manzi, Susan (author)
  • Urowitz, Murray B. (author)
  • Gladman, Dafna (author)
  • Fortin, Paul R. (author)
  • Ginzler, Ellen M. (author)
  • Yelin, Edward (author)
  • Bae, Sang-Cheol (author)
  • Wallace, Daniel J. (author)
  • Jacobsen, Soren (author)
  • Dooley, Mary Anne (author)
  • Peschken, Christine A. (author)
  • Alarcon, Graciela S. (author)
  • Nived, OlaLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)reum-oni (author)
  • Gottesman, Lena (author)
  • Criswell, Lindsey A. (author)
  • Sturfelt, GunnarLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)reum-gst (author)
  • Dreyer, Lene (author)
  • Lee, Jennifer L. (author)
  • Clarke, Ann E. (author)
  • Reumatologi och molekylär skelettbiologiSektion III (creator_code:org_t)

Related titles

  • In:Oncology: S. Karger AG85:4, s. 235-2401423-02320030-2414

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