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Age-specific season...
Age-specific seasonal influenza vaccine effectiveness against different influenza subtypes in the hospitalized population in lithuania during the 2015–2019 influenza seasons
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- Kuliese, Monika (författare)
- Lithuanian University of Health Sciences
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- Mickiene, Aukse (författare)
- Lithuanian University of Health Sciences
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- Jancoriene, Ligita (författare)
- Vilnius University
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- Zablockiene, Birute (författare)
- Vilnius University
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- Gefenaite, Giedre (författare)
- Lund University,Lunds universitet,Aktivt och hälsosamt åldrande,Forskargrupper vid Lunds universitet,Active and Healthy Ageing Research Group,Lund University Research Groups,Lithuanian University of Health Sciences
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(creator_code:org_t)
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- 2021-05-04
- 2021
- Engelska.
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Ingår i: Vaccines. - : MDPI AG. - 2076-393X. ; 9:5
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://www.mdpi.com...
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https://lup.lub.lu.s...
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https://doi.org/10.3...
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Abstract
Ämnesord
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- Background: Continuous monitoring of seasonal influenza vaccine effectiveness (SIVE) is needed due to the changing nature of influenza viruses and it supports the decision on the annual update of vaccine composition. Age-specific SIVE was evaluated against different influenza sub-types in the hospitalized population in Lithuania during four influenza seasons. Methods: A test-negative case-control study design was used. SIVE and its 95% confidence intervals (95% CI) were calculated as (1 – odds ratio (OR)) × 100%. Results: Adjusted SIVE in 18–64-year-old individuals against influenza A, A(H1N1)pdm09 and B/Yamagata were 78.0% (95% CI: 1.7; 95.1%), 88.6% (95% CI: −47.4; 99.1%), and 76.8% (95% CI: −109.9; 97.4%), respectively. Adjusted SIVE in individuals aged 65 years and older against influenza A, influenza B, and B/Yamagata were 22.6% (95% CI: −36.5; 56.1%), 75.3% (95% CI: 12.2; 93.1%) and 73.1% (95% CI: 3.2; 92.5%), respectively. Unadjusted SIVE against influenza A(H3N2) among 18–64-year-old patients was 44.8% (95% CI: −171.0; 88.8%) and among those aged 65 years and older was 5.0% (95% CI: −74.5; 48.3%). Conclusions: Point estimates suggest high SIVE against influenza A in 18–64-year-old participants, and against influenza B and B/Yamagata in those 65 years old and older.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Hospital surveillance
- Influenza
- Laboratory-confirmed
- Older people
- Risk groups
- Severe outcomes
- Underlying conditions
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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