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Oral contraceptives...
Oral contraceptives, reproductive history and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition
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Tsilidis, K. K. (author)
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Allen, N. E. (author)
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Key, T. J. (author)
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show more...
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Bakken, K. (author)
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Lund, E. (author)
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Berrino, F. (author)
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Fournier, A. (author)
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Olsen, A. (author)
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Tjonneland, A. (author)
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Overvad, K. (author)
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Boutron-Ruault, M-C (author)
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Clavel-Chapelon, F. (author)
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Byrnes, G. (author)
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Chajes, V. (author)
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Rinaldi, S. (author)
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Chang-Claude, J. (author)
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Kaaks, R. (author)
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Bergmann, M. (author)
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Boeing, H. (author)
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Koumantaki, Y. (author)
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Stasinopoulou, G. (author)
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Trichopoulou, A. (author)
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Palli, D. (author)
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Tagliabue, G. (author)
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Panico, S. (author)
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Tumino, R. (author)
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Vineis, P. (author)
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Bueno-de-Mesquita, H. B. (author)
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van Duijnhoven, F. J. B. (author)
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van Gils, C. H. (author)
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Peeters, P. H. M. (author)
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Rodriguez, L. (author)
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Gonzalez, C. A. (author)
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Sanchez, M-J (author)
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Chirlaque, M-D (author)
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Barricarte, A. (author)
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Dorronsoro, M. (author)
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- Borgquist, Signe (author)
- Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Manjer, Jonas (author)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- van Guelpen, Bethany (author)
- Umeå universitet,Patologi
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- Hallmans, Göran, 1947- (author)
- Umeå universitet,Näringsforskning
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Rodwell, S. A. (author)
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Khaw, K-T (author)
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Norat, T. (author)
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Romaguera, D. (author)
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Riboli, E. (author)
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(creator_code:org_t)
- 2010-11-02
- 2010
- English.
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In: British Journal of Cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 103:11, s. 1755-1759
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Abstract
Subject headings
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- BACKGROUND: Oral contraceptive use and reproductive factors may initiate long-term changes to the hormonal milieu and thereby, possibly influence colorectal cancer risk. METHODS: We examined the association of hormonal and reproductive factors with risk of colorectal cancer among 337 802 women in the European Prospective Investigation into Cancer and Nutrition, of whom 1878 developed colorectal cancer. RESULTS: After stratification for center and age, and adjustment for body mass index, smoking, diabetes mellitus, physical activity and alcohol consumption, ever use of oral contraceptives was marginally inversely associated with colorectal cancer risk (hazard ratio (HR), 0.92; 95% confidence interval (CI), 0.83-1.02), although this association was stronger among post-menopausal women (HR, 0.84; 95% CI: 0.74-0.95). Duration of oral contraceptive use and reproductive factors, including age at menarche, age at menopause, type of menopause, ever having an abortion, parity, age at first full-term pregnancy and breastfeeding, were not associated with colorectal cancer risk. CONCLUSION: Our findings provide limited support for a potential inverse association between oral contraceptives and colorectal cancer risk. British Journal of Cancer (2010) 103, 1755-1759. doi:10.1038/sj.bjc.6605965 www.bjcancer.com Published online 2 November 2010 (C) 2010 Cancer Research UK
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- cohort
- colorectal cancer
- oral contraceptives
- reproductive history
- study
- oral contraceptives
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Tsilidis, K. K.
-
Allen, N. E.
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Key, T. J.
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Bakken, K.
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Lund, E.
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Berrino, F.
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show more...
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Fournier, A.
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Olsen, A.
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Tjonneland, A.
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Overvad, K.
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Boutron-Ruault, ...
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Clavel-Chapelon, ...
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Byrnes, G.
-
Chajes, V.
-
Rinaldi, S.
-
Chang-Claude, J.
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Kaaks, R.
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Bergmann, M.
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Boeing, H.
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Koumantaki, Y.
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Stasinopoulou, G ...
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Trichopoulou, A.
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Palli, D.
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Tagliabue, G.
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Panico, S.
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Tumino, R.
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Vineis, P.
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Bueno-de-Mesquit ...
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van Duijnhoven, ...
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van Gils, C. H.
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Peeters, P. H. M ...
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Rodriguez, L.
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Gonzalez, C. A.
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Sanchez, M-J
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Chirlaque, M-D
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Barricarte, A.
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Dorronsoro, M.
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Borgquist, Signe
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Manjer, Jonas
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van Guelpen, Bet ...
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Hallmans, Göran, ...
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Rodwell, S. A.
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Khaw, K-T
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Norat, T.
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Romaguera, D.
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Riboli, E.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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British Journal ...
- By the university
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Lund University
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Umeå University