Sökning: WFRF:(Karlén A.)
> (2015-2019) >
Venous thrombosis i...
Venous thrombosis in children and adolescents with Hodgkin lymphoma in Sweden
-
- Schönning, A. (författare)
- Karolinska Institute,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
-
- Karlén, J. (författare)
- Karolinska Institute,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
-
- Frisk, T (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
-
visa fler...
-
- Heyman, M M (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
-
- Svahn, J. E. (författare)
- Lund University,Lunds universitet,Pediatrisk onkologi,Forskargrupper vid Lunds universitet,Pediatric Oncology,Lund University Research Groups,Skåne University Hospital,Lund University, Sweden
-
- Øra, I. (författare)
- Lund University,Lunds universitet,Pediatrisk onkologi,Forskargrupper vid Lunds universitet,Pediatric Oncology,Lund University Research Groups,Skåne University Hospital,Lund University, Sweden
-
- Kawan, L. (författare)
- Sahlgrens University Hospital, Sweden
-
- Holmqvist Persson, Britt-Marie (författare)
- Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Region Östergötland, Barn- och ungdomskliniken i Linköping,Linköping University Hospital
-
- Björklund, C. (författare)
- Norrland University Hospital,Umeå University Hospital, Sweden
-
- Harila-Saari, Arja (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
-
- Ranta, S (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
-
visa färre...
-
(creator_code:org_t)
- Elsevier BV, 2017
- 2017
- Engelska 5 s.
-
Ingår i: Thrombosis Research. - : Elsevier BV. - 0049-3848 .- 1879-2472. ; 152, s. 64-68
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Introduction Pediatric patients with Hodgkin lymphoma (HL) have several risk factors for venous thromboembolism (VTE). Although these patients are occasionally treated with thromboprophylaxis, no guidelines are implemented in Sweden. Scarce data from adult patients indicate an increased risk of VTE, but pediatric data is largely missing. Given the favorable overall survival of HL, there should reasonably be more focus on preventing complications. Materials and methods We conducted a retrospective cohort study, including all patients registered in the Childhood Cancer Registry under the age of 18 years diagnosed with HL between January 2005 and December 2015 in Sweden. Results Data was retrieved from the medical records of all 163 patients (100%) at six Swedish pediatric cancer centers. The incidence of VTE was 7.7% (symptomatic VTE 3.9%). The median follow-up was 3.4 years (range 0.3–10.5). Only five patients (3.1%) were treated with thromboprophylaxis. All VTE events occurred in the older age category (11–17 years) and all but one (92.7%) had a mediastinal mass. While the VTE did not significantly affect the treatment of HL, it caused increased morbidity and 2/12 developed a post-thrombotic syndrome. No significant risk factors for VTE were identified. Conclusions VTE is a relatively common complication of HL and its treatment, causing increased acute and long-term morbidity. However, due to limited number of events we could not demonstrate risk-factors for VTE that would identify patients who might benefit from thromboprophylaxis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Adolescents
- Children
- Hodgkin lymphoma
- Venous thromboembolism
- Hodgkin lymphoma; Venous thromboembolism; Children; Adolescents
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Schönning, A.
-
Karlén, J.
-
Frisk, T
-
Heyman, M M
-
Svahn, J. E.
-
Øra, I.
-
visa fler...
-
Kawan, L.
-
Holmqvist Persso ...
-
Björklund, C.
-
Harila-Saari, Ar ...
-
Ranta, S
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Hematologi
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Cancer och onkol ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Kirurgi
- Artiklar i publikationen
-
Thrombosis Resea ...
- Av lärosätet
-
Lunds universitet
-
Linköpings universitet
-
Karolinska Institutet