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- Sera, Terez (författare)
Multicentre Studies
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- Artikel/kapitelEngelska2022
Förlag, utgivningsår, omfång ...
- 2022
- 16 s.
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- LIBRIS-ID:oai:lup.lub.lu.se:26ce9e9c-15f4-4763-b462-90e7de9f32d9
- https://lup.lub.lu.se/record/26ce9e9c-15f4-4763-b462-90e7de9f32d9URI
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- Språk:engelska
- Sammanfattning på:engelska
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- The first part of the chapter provides an introduction on the implementation of quality-assurance programmes in nuclear medicine (NM) services. It is argued that participation in interlaboratory comparisons has two main benefits. First, on top of existing local quality-assurance programmes, participation can add a level of reassurance on quality. Second, interlaboratory comparisons are prerequisite for clinical multicentre trials. The success of an interlaboratory comparison depends on many parameters, this chapter will discuss financing, selection, and procurement of the quality-control devices and selection of participants. The discussion on the execution and evaluation of a multicentre study is followed by the presentation of potential problems and recommendations on how to avoid them. The chapter discusses the most widely known interlaboratory quality-assurance programmes, including the EANM/EARL 18-F FDG PET/CT accreditation programme and the DAT-Scan SPECT standardization programme. In the second part, examples of multicentre studies, based on Monte-Carlo simulated scintillation camera imaging and a computer phantom, with the aims of investigating how different clinical sites perform evaluation using the routine. These studies started in Sweden 2012 and have included renography, bone scintigraphy, lung scintigraphy, and myocardial studies. The camera- and acquisition parameters for each site were considered, and images were distributed by Dicom files to be read in and processed as they were coming from the site’s own camera. The outcome from the evaluation was then compared to the truth (i.e., the known disease, abnormality, change in function) as defined by the activity distribution in the computer phantom.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
- Boellaard, RonaldAmsterdam UMC - Vrije Universiteit Amsterdam,Vrije Universiteit Amsterdam,Academic Medical Center of University of Amsterdam (AMC),Chinese University of Hong Kong (författare)
- Kaalep, Andres (författare)
- Ljungberg, MichaelLund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nuclear Medicine Physics,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups(Swepub:lu)rafy-mlj (författare)
- Ljungberg, Michael (redaktör/utgivare)
- Amsterdam UMC - Vrije Universiteit AmsterdamVrije Universiteit Amsterdam (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures - Instrumentation and Imaging Procedures197811385932689780429489556
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