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Feedback interstitial diode laser (805 nm) thermotherapy system: Ex vivo evaluation and mathematical modeling with one and four-fibers
- Artikel/kapitelEngelska1998
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LIBRIS-ID:oai:lup.lub.lu.se:29291337-de7b-48af-9a9c-69d1c6fab51c
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https://lup.lub.lu.se/record/2258426URI
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https://doi.org/10.1002/(SICI)1096-9101(1998)22:2<86::AID-LSM4>3.0.CO;2-SDOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
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Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in ground bovine muscle using either a single laser fiber or four-fibers. The target temperature at one (feedback) thermistor, placed 5 mm from one of the laser fibers, was set to 50 degrees C and was maintained by means of stepwise power regulation. The temperature distribution was monitored using multiple thermistor probes. A numerical model based on the bioheat equation was used to calculate the temperature distributions. Results: Temperature regulation was excellent with a tendency towards better regulation in the four-fiber than in the single-fiber experiments. Agreement between calculated and measured temperatures was good. The coagulated (>55 degrees C) and hyperthermic (>45 degrees C) volumes were 6 and 10-11 times larger, respectively, with four-fibers than with a single fiber. Conclusion: It is concluded that the stepwise power regulation system was efficient in maintaining a stable target temperature. The results indicate that the system can produce lesion volumes adequate for treating a relatively large tumor in a single session and that computer simulation may be useful for predicting temperature distribution. (C) 1998 Wiley-Liss, Inc.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Olsrud, J
(författare)
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Sturesson, C
(författare)
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Moller, P. H
(författare)
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Persson, Bertil RLund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)radf-bpe
(författare)
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Tranberg, K. G
(författare)
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Medicinsk strålningsfysik, LundSektion V
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Lasers in Surgery and Medicine22:2, s. 86-960196-8092
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