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Postural orthostati...
Postural orthostatic tachycardia syndrome (POTS) : State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1
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- Vernino, Steven (author)
- University of Texas Southwestern Medical Center
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- Bourne, Kate M. (author)
- University of Calgary
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- Stiles, Lauren E. (author)
- Dysautonomia International,Stony Brook University
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- Grubb, Blair P. (author)
- The University of Toledo Medical Center
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- Fedorowski, Artur (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital
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- Stewart, Julian M. (author)
- New York Medical College
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- Arnold, Amy C. (author)
- Pennsylvania State University,Vanderbilt University
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- Pace, Laura A. (author)
- University of Utah
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- Axelsson, Jonas (author)
- Karolinska University Hospital
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- Boris, Jeffrey R. (author)
- Jeffrey R Boris MD LLC
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- Moak, Jeffrey P. (author)
- George Washington University
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- Goodman, Brent P. (author)
- Mayo Clinic Scottsdale-Phoenix, Arizona
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- Chémali, Kamal R. (author)
- Sentara Healthcare
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- Chung, Tae H. (author)
- Johns Hopkins University School of Medicine
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- Goldstein, David S. (author)
- National Institutes of Health, United States
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- Diedrich, Andre (author)
- Vanderbilt University
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- Miglis, Mitchell G. (author)
- Stanford University
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- Cortez, Melissa M. (author)
- University of Utah
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- Miller, Amanda J. (author)
- Pennsylvania State University
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- Freeman, Roy (author)
- Harvard Medical School,Beth Israel Deaconess Medical Center
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- Biaggioni, Italo (author)
- Vanderbilt University
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- Rowe, Peter C. (author)
- Johns Hopkins University
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- Sheldon, Robert S. (author)
- University of Calgary
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- Shibao, Cyndya A. (author)
- Vanderbilt University
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- Systrom, David M. (author)
- Harvard Medical School
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- Cook, Glen A. (author)
- Uniformed Services University of the Health Sciences
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- Doherty, Taylor A. (author)
- University of California, San Diego
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- Abdallah, Hasan I. (author)
- Children's Heart Institute
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- Darbari, Anil (author)
- George Washington University
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- Raj, Satish R. (author)
- University of Calgary
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(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- English.
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In: Autonomic Neuroscience: Basic and Clinical. - : Elsevier BV. - 1566-0702. ; 235
- Related links:
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http://dx.doi.org/10... (free)
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http://www.autonomic...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by orthostatic intolerance with excessive heart rate increase without hypotension during upright posture. Patients often experience a constellation of other typical symptoms including fatigue, exercise intolerance and gastrointestinal distress. A typical patient with POTS is a female of child-bearing age, who often first displays symptoms in adolescence. The onset of POTS may be precipitated by immunological stressors such as a viral infection. A variety of pathophysiologies are involved in the abnormal postural tachycardia response; however, the pathophysiology of the syndrome is incompletely understood and undoubtedly multifaceted. Clinicians and researchers focused on POTS convened at the National Institutes of Health in July 2019 to discuss the current state of understanding of the pathophysiology of POTS and to identify priorities for POTS research. This article, the first of two articles summarizing the information discussed at this meeting, summarizes the current understanding of this disorder and best practices for clinical care. The evaluation of a patient with suspected POTS should seek to establish the diagnosis, identify co-morbid conditions, and exclude conditions that could cause or mimic the syndrome. Once diagnosed, management typically begins with patient education and non-pharmacologic treatment options. Various medications are often used to address specific symptoms, but there are currently no FDA-approved medications for the treatment of POTS, and evidence for many of the medications used to treat POTS is not robust.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Expert consensus
- Pathophysiology
- Postural orthostatic tachycardia syndrome
- Treatment
- Workshop
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Vernino, Steven
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Bourne, Kate M.
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Stiles, Lauren E ...
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Grubb, Blair P.
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Fedorowski, Artu ...
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Stewart, Julian ...
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show more...
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Arnold, Amy C.
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Pace, Laura A.
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Axelsson, Jonas
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Boris, Jeffrey R ...
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Moak, Jeffrey P.
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Goodman, Brent P ...
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Chémali, Kamal R ...
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Chung, Tae H.
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Goldstein, David ...
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Diedrich, Andre
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Miglis, Mitchell ...
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Cortez, Melissa ...
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Miller, Amanda J ...
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Freeman, Roy
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Biaggioni, Italo
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Rowe, Peter C.
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Sheldon, Robert ...
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Shibao, Cyndya A ...
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Systrom, David M ...
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Cook, Glen A.
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Doherty, Taylor ...
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Abdallah, Hasan ...
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Darbari, Anil
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Raj, Satish R.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Autonomic Neuros ...
- By the university
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Lund University