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  • Abdollahi, SaraFerdowsi University of Mashhad,Reza Radiotherapy and Oncology Center (author)

Surface guided 3DCRT in deep-inspiration breath-hold for left sided breast cancer radiotherapy : implementation and first clinical experience in Iran

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • 2022
  • 16 s.

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:2aa1a694-00f3-4b85-a948-5b956cefdf4a
  • https://lup.lub.lu.se/record/2aa1a694-00f3-4b85-a948-5b956cefdf4aURI
  • https://doi.org/10.5603/rpOr.a2022.0103DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Background: The aim of the study is to evaluate the overall accuracy of the surface-guided radiotherapy (SGRT) workflow through a comprehensive commissioning and quality assurance procedures and assess the potential benefits of deep-inspiration breath-hold (DIBH) radiotherapy as a cardiac and lung dose reduction approach for left-sided breast cancer irradiation. Materials and methods: Accuracy and reproducibility of the optical surface scanner used for DIBH treatment were evaluated using different phantoms. Patient positioning accuracy and reproducibility of DIBH treatment were evaluated. Twenty patients were studied for treatment plan quality in target dose coverage and healthy organ sparing for the two different treatment techniques. Results: Reproducibility tests for the surface scanner showed good stability within 1 mm in all directions. The maximum position variation between applied shifts on the couch and the scanner measured offsets is 1 mm in all directions. The clinical study of 200 fractions showed good agreement between the surface scanner and portal imaging with the isocenter position deviation of less than 3 mm in each lateral, longitudinal, and vertical direction. The standard deviation of the DIBH level showed a value of < 2 mm during all evaluated DIBHs. Compared to the free breathing (FB) technique, DIBH showed significant reduction of 48% for heart mean dose, 43% for heart V25, and 20% for ipsilateral lung V20. Conclusion: Surface-guided radiotherapy can be regarded as an accurate tool for patient positioning and monitoring in breast radiotherapy. DIBH treatment are considered to be effective techniques in heart and ipsilateral lung dose reductions for left breast radiotherapy.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Yazdi, Mohammad Hadi HadizadehFerdowsi University of Mashhad (author)
  • Mowlavi, Ali AsgharFerdowsi University of Mashhad (author)
  • Ceberg, SofieLund University,Lunds universitet,Radiotherapy Physics,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments(Swepub:lu)med-sem (author)
  • Aznar, Marianne CamilleUniversity of Manchester (author)
  • Tabrizi, Fatemeh VarshoeeReza Radiotherapy and Oncology Center (author)
  • Salek, RohamReza Radiotherapy and Oncology Center,Mashhad University of Medical Sciences (author)
  • Ghodsi, AlirezaHakim Sabzevari University (author)
  • Jamali, FaridehReza Radiotherapy and Oncology Center (author)
  • Ferdowsi University of MashhadReza Radiotherapy and Oncology Center (creator_code:org_t)

Related titles

  • In:Reports of Practical Oncology and Radiotherapy27:5, s. 881-8961507-1367

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