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Sökning: WFRF:(Voskuyl Alexandre E.) > Belimumab concentra...

  • Loeff, Floris C.Biologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands (författare)

Belimumab concentration measurements using a homologous anti-idiotype immunoassay

  • Artikel/kapitelEngelska2024

Förlag, utgivningsår, omfång ...

  • 2024
  • Elsevier,2024
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-114616
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-114616URI
  • https://doi.org/10.1016/j.jim.2024.113717DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Monitoring belimumab concentrations in patients can be a valuable tool for assessing treatment response and for personalizing drug doses. Various assay formats may be used to measure concentrations of therapeutic monoclonal antibodies. A particularly useful format involves the use of anti-idiotype monoclonal antibodies, selected to be highly specific to the antibody of interest. Here, we describe the development of a specific, high-affinity anti-idiotype antibody to belimumab, and the application of this antibody in a homologous sandwich ELISA to measure belimumab concentrations.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Parodis, Ioannis,1981-Örebro universitet,Institutionen för medicinska vetenskaper,Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden; Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden(Swepub:oru)isps (författare)
  • Walhelm, TomasDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden (författare)
  • Jönsen, AndreasDepartment of Clinical Sciences Lund, Rheumatology, Lund University, Skåne University Hospital, Lund, Sweden (författare)
  • Nikolopoulos, DionysisDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden (författare)
  • Sjöwall, ChristopherDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden (författare)
  • Bengtsson, Anders A.Department of Clinical Sciences Lund, Rheumatology, Lund University, Skåne University Hospital, Lund, Sweden (författare)
  • Kos, DorienSanquin Reagents B.V., Amsterdam, the Netherlands (författare)
  • van Leeuwen, AstridBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands (författare)
  • van den Broek, BryanBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands (författare)
  • Dijk, LisanneBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands (författare)
  • Jeremiasse, JornBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands (författare)
  • Blomjous, Birgit S.Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam University Medical Center, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands (författare)
  • Voskuyl, Alexandre E.Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam University Medical Center, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands (författare)
  • Wolbink, Gerrit JanAmsterdam Rheumatology and immunology Center|Reade, Amsterdam, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (författare)
  • Bultink, Irene E. M.Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam University Medical Center, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands (författare)
  • Rispens, TheoBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (författare)
  • Biologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the NetherlandsInstitutionen för medicinska vetenskaper (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:JIM - Journal of Immunological Methods: Elsevier0022-17591872-7905

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