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Belimumab concentra...
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Loeff, Floris C.Biologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands
(författare)
Belimumab concentration measurements using a homologous anti-idiotype immunoassay
- Artikel/kapitelEngelska2024
Förlag, utgivningsår, omfång ...
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2024
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Elsevier,2024
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-114616
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-114616URI
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https://doi.org/10.1016/j.jim.2024.113717DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Monitoring belimumab concentrations in patients can be a valuable tool for assessing treatment response and for personalizing drug doses. Various assay formats may be used to measure concentrations of therapeutic monoclonal antibodies. A particularly useful format involves the use of anti-idiotype monoclonal antibodies, selected to be highly specific to the antibody of interest. Here, we describe the development of a specific, high-affinity anti-idiotype antibody to belimumab, and the application of this antibody in a homologous sandwich ELISA to measure belimumab concentrations.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Parodis, Ioannis,1981-Örebro universitet,Institutionen för medicinska vetenskaper,Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden; Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden(Swepub:oru)isps
(författare)
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Walhelm, TomasDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden
(författare)
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Jönsen, AndreasDepartment of Clinical Sciences Lund, Rheumatology, Lund University, Skåne University Hospital, Lund, Sweden
(författare)
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Nikolopoulos, DionysisDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology, Dermatology and Rheumatology, Karolinska University Hospital, Stockholm, Sweden
(författare)
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Sjöwall, ChristopherDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden
(författare)
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Bengtsson, Anders A.Department of Clinical Sciences Lund, Rheumatology, Lund University, Skåne University Hospital, Lund, Sweden
(författare)
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Kos, DorienSanquin Reagents B.V., Amsterdam, the Netherlands
(författare)
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van Leeuwen, AstridBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands
(författare)
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van den Broek, BryanBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands
(författare)
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Dijk, LisanneBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands
(författare)
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Jeremiasse, JornBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands
(författare)
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Blomjous, Birgit S.Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam University Medical Center, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands
(författare)
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Voskuyl, Alexandre E.Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam University Medical Center, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands
(författare)
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Wolbink, Gerrit JanAmsterdam Rheumatology and immunology Center|Reade, Amsterdam, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands
(författare)
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Bultink, Irene E. M.Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam University Medical Center, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands
(författare)
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Rispens, TheoBiologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands
(författare)
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Biologics Laboratory, Sanquin Diagnostic Services, Amsterdam, the NetherlandsInstitutionen för medicinska vetenskaper
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:JIM - Journal of Immunological Methods: Elsevier0022-17591872-7905
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Loeff, Floris C.
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Parodis, Ioannis ...
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Walhelm, Tomas
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Jönsen, Andreas
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Nikolopoulos, Di ...
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Sjöwall, Christo ...
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visa fler...
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Bengtsson, Ander ...
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Kos, Dorien
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van Leeuwen, Ast ...
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van den Broek, B ...
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Dijk, Lisanne
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Jeremiasse, Jorn
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Blomjous, Birgit ...
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Voskuyl, Alexand ...
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Wolbink, Gerrit ...
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Bultink, Irene E ...
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Rispens, Theo
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Örebro universitet