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Sökning: WFRF:(Ourselin Sebastien) > (2020-2022) > Symptoms and syndro...

Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts

Molteni, Erika (författare)
King's College London,Kings Coll London, Sch Biomed Engn & Imaging Sci, 9th Floor,Becket House,1 Lambeth Palace Rd, London SE1 7EU, England.
Astley, Christina M. (författare)
Harvard University,Boston Children's Hospital,Boston Childrens Hosp, Boston, MA USA.;Harvard Med Sch, Boston, MA 02115 USA.,Kings Coll London, Sch Biomed Engn & Imaging Sci, 9th Floor,Becket House,1 Lambeth Palace Rd, London SE1 7EU, England.
Ma, Wenjie (författare)
Massachusetts General Hospital,Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.
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Sudre, Carole H. (författare)
King's College London,Kings Coll London, Sch Biomed Engn & Imaging Sci, 9th Floor,Becket House,1 Lambeth Palace Rd, London SE1 7EU, England.
Magee, Laura A. (författare)
King's College London,Kings Coll London, Sch Life Course Sci, Dept Women & Childrens Hlth, London, England.;Kings Coll London, Inst Women & Childrens Hlth, London, England.
Murray, Benjamin (författare)
King's College London,Kings Coll London, Sch Biomed Engn & Imaging Sci, 9th Floor,Becket House,1 Lambeth Palace Rd, London SE1 7EU, England.
Fall, Tove (författare)
Uppsala universitet,Uppsala University,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi
Gomez, Maria F. (författare)
Lund University,Lunds universitet,Diabetiska komplikationer,Forskargrupper vid Lunds universitet,Diabetic Complications,Lund University Research Groups,Lund Univ, Dept Clin Sci, Diabet Ctr, Jan Waldenstroms Gata 35, S-21428 Malmö, Sweden.
Tsereteli, Neli (författare)
Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Lund Univ, Dept Clin Sci, Diabet Ctr, Jan Waldenstroms Gata 35, S-21428 Malmö, Sweden.
Franks, Paul W. (författare)
Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Lund Univ, Dept Clin Sci, Diabet Ctr, Jan Waldenstroms Gata 35, S-21428 Malmö, Sweden.
Brownstein, John S. (författare)
Boston Children's Hospital,Harvard University,Boston Childrens Hosp, Boston, MA USA.;Harvard Med Sch, Boston, MA 02115 USA.
Davies, Richard (författare)
Zoe Global Limited,Zoe Global Ltd, London, England.
Wolf, Jonathan (författare)
Zoe Global Limited,Zoe Global Ltd, London, England.
Spector, Tim D. (författare)
King's College London,Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.
Ourselin, Sebastien (författare)
King's College London,Kings Coll London, Sch Biomed Engn & Imaging Sci, 9th Floor,Becket House,1 Lambeth Palace Rd, London SE1 7EU, England.
Steves, Claire J. (författare)
King's College London,Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.
Chan, Andrew T. (författare)
Massachusetts General Hospital,Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.
Modat, Marc (författare)
King's College London
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King's College London Kings Coll London, Sch Biomed Engn & Imaging Sci, 9th Floor,Becket House,1 Lambeth Palace Rd, London SE1 7EU, England (creator_code:org_t)
2021-03-25
2021
Engelska.
Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 11:1
Relaterad länk:
http://dx.doi.org/10... (free)
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https://www.nature.c...
https://doi.org/10.1...
https://uu.diva-port... (primary) (Raw object)
https://lup.lub.lu.s...
https://doi.org/10.1...
https://urn.kb.se/re...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • We tested whether pregnant and non-pregnant women differ in COVID-19 symptom profile and severity, and we extended previous investigations on hospitalized pregnant women to those who did not require hospitalization. Two female community-based cohorts (18–44 years) provided longitudinal (smartphone application, N = 1,170,315, n = 79 pregnant tested positive) and cross-sectional (web-based survey, N = 1,344,966, n = 134 pregnant tested positive) data, prospectively collected through self-participatory citizen surveillance in UK, Sweden and USA. Pregnant and non-pregnant were compared for frequencies of events, including SARS-CoV-2 testing, symptoms and hospitalization rates. Multivariable regression was used to investigate symptoms severity and comorbidity effects. Pregnant and non-pregnant women positive for SARS-CoV-2 infection were not different in syndromic severity, except for gastrointestinal symptoms. Pregnant were more likely to have received testing, despite reporting fewer symptoms. Pre-existing lung disease was most closely associated with syndromic severity in pregnant hospitalized. Heart and kidney diseases and diabetes increased risk. The most frequent symptoms among non-hospitalized women were anosmia [63% pregnant, 92% non-pregnant] and headache [72%, 62%]. Cardiopulmonary symptoms, including persistent cough [80%] and chest pain [73%], were more frequent among pregnant who were hospitalized. Consistent with observations in non-pregnant populations, lung disease and diabetes were associated with increased risk of more severe SARS-CoV-2 infection during pregnancy.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

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