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Wirfält, ElisabetLund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
(författare)
Associations between food patterns defined by cluster analysis and colorectal cancer incidence in the NIH-AARP diet and health study.
- Artikel/kapitelEngelska2009
Förlag, utgivningsår, omfång ...
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2008-08-06
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Springer Science and Business Media LLC,2009
Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:2cfd6e6e-d6fa-497c-95fb-01eb38cea92d
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https://lup.lub.lu.se/record/1223409URI
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https://doi.org/10.1038/ejcn.2008.40DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
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Background/Objectives:To examine associations between food patterns, constructed with cluster analysis, and colorectal cancer incidence within the National Institutes of Health-AARP Diet and Health Study.Subjects/Methods:A prospective cohort, aged 50-71 years at baseline in 1995-1996, followed until the end of 2000. Food patterns were constructed, separately in men (n=293 576) and women (n=198 730), with 181 food variables (daily intake frequency per 1000 kcal) from a food frequency questionnaire. Four large clusters were identified in men and three in women. Cox proportional hazards regression examined associations between patterns and cancer incidence.Results:In men, a vegetable and fruit pattern was associated with reduced colorectal cancer incidence (multivariate hazard ratio, HR: 0.85; 95% confidence interval, CI: 0.76, 0.94), when compared to less salutary food choices. Both the vegetable and fruit pattern and a fat-reduced foods pattern were associated with reduced rectal cancer incidence in men. In women, a similar vegetable and fruit pattern was associated with colorectal cancer protection (age-adjusted HR: 0.82; 95% CI: 0.70, 0.95), but the association was not statistically significant in multivariate analysis.Conclusions:These results, together with findings from previous studies support the hypothesis that micronutrient dense, low-fat, high-fiber food patterns protect against colorectal cancer.European Journal of Clinical Nutrition advance online publication, 6 August 2008; doi:10.1038/ejcn.2008.40.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Midthune, D
(författare)
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Reedy, J
(författare)
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Mitrou, P
(författare)
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Flood, A
(författare)
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Subar, A F
(författare)
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Leitzmann, M
(författare)
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Mouw, T
(författare)
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Hollenbeck, A R
(författare)
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Schatzkin, A
(författare)
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Kipnis, V
(författare)
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NutritionsepidemiologiForskargrupper vid Lunds universitet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:European Journal of Clinical Nutrition: Springer Science and Business Media LLC63, s. 707-7171476-56400954-3007
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Wirfält, Elisabe ...
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Midthune, D
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Reedy, J
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Mitrou, P
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Flood, A
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Subar, A F
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visa fler...
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Leitzmann, M
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Mouw, T
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Hollenbeck, A R
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Schatzkin, A
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Kipnis, V
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