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  • Singh, BirendraLund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups (author)

Vitronectin in host pathogen interactions and antimicrobial therapeutic applications

  • Article/chapterEnglish2011

Publisher, publication year, extent ...

  • 2011-11-23
  • Walter de Gruyter GmbH,2011
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:2f98cfc8-45a5-420c-abd2-65dbe9780578
  • https://lup.lub.lu.se/record/2272195URI
  • https://doi.org/10.2478/s11535-011-0077-xDOI

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  • Language:English
  • Summary in:English

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  • Subject category:for swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Vitronectin (Vn) is a multifunctional glycoprotein profusely present in serum and bound to epithelial cell surfaces. It plays an important role in cell migration, tissue repair and regulation of membrane attack complex (MAC) formation. In the last decade the role of Vn has been extensively investigated in eukaryotic signalling and cell migration leading to the possibility of developing novel anticancer drugs. In parallel, several studies have suggested that pathogens utilize Vn in invasion of the host. Here we review the properties of Vn and its role in host-pathogen interactions that might be a future target for therapeutic intervention.

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  • Su, Yu-ChingLund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-s_s (author)
  • Riesbeck, KristianLund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups(Swepub:lu)mikr-kri (author)
  • Klinisk mikrobiologi, MalmöForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Central European Journal of Biology: Walter de Gruyter GmbH6:6, s. 973-9801895-104X
  • In:Open Life Sciences: Walter de Gruyter GmbH6:6, s. 973-9802391-5412

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MEDICAL AND HEALTH SCIENCES
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