Search: L773:1895 104X OR L773:1644 3632 >
Vitronectin in host...
Vitronectin in host pathogen interactions and antimicrobial therapeutic applications
-
- Singh, Birendra (author)
- Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups
-
- Su, Yu-Ching (author)
- Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups,Skåne University Hospital
-
- Riesbeck, Kristian (author)
- Lund University,Lunds universitet,Klinisk mikrobiologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Microbiology, Malmö,Lund University Research Groups
-
(creator_code:org_t)
- 2011-11-23
- 2011
- English.
-
In: Central European Journal of Biology. - : Walter de Gruyter GmbH. - 1895-104X. ; 6:6, s. 973-980
- Related links:
-
https://portal.resea... (primary) (free)
-
show more...
-
http://dx.doi.org/10...
-
https://lup.lub.lu.s...
-
https://lup.lub.lu.s...
-
https://doi.org/10.2...
-
show less...
Abstract
Subject headings
Close
- Vitronectin (Vn) is a multifunctional glycoprotein profusely present in serum and bound to epithelial cell surfaces. It plays an important role in cell migration, tissue repair and regulation of membrane attack complex (MAC) formation. In the last decade the role of Vn has been extensively investigated in eukaryotic signalling and cell migration leading to the possibility of developing novel anticancer drugs. In parallel, several studies have suggested that pathogens utilize Vn in invasion of the host. Here we review the properties of Vn and its role in host-pathogen interactions that might be a future target for therapeutic intervention.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- Bacteria
- Complement system
- Extracellular matrix
- Innate immunity
- Integrins
- Vitronectin
Publication and Content Type
- for (subject category)
- ref (subject category)
Find in a library
To the university's database