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Integrated system f...
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Andersson-Engels, StefanLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
(författare)
Integrated system for interstitial photodynamic therapy
- Artikel/kapitelEngelska2002
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Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:34775c42-484c-4741-869f-d2c8753cb13a
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https://lup.lub.lu.se/record/1407040URI
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https://lup.lub.lu.se/record/1126731URI
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https://doi.org/10.1117/12.517035DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:kon swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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To develop PDT beyond treatment of thin superficial tumours, to also be an efficient treatment alternative for deeply located and/or thick tumours, a system based on interstitial illumination using multiple fibres has been developed. Conditions that could benefit from such a treatment modality are for instance malignant brain tumours and tumours in the oral cavity. In interstitial PDT one needs to use multiple fibres for light delivery in order to allow treatments of tumours larger than a few millimetres in diameter. Our system consists of a laser light source, a beam-splitting system dividing the light into three or six output fibres and a custom-made dosimetry programme. The concept is then to use these fibres not only for delivering the treatment light but also to measure parameters of interest for the treatment outcome. The fluence rate of the light emitted by each fibre is measured at the positions of the other fibre tips. From these results the light dose at all positions could be recalculated. Changes in optical properties as well as bleaching and concentration of the photosensitizer during the treatment could be monitored and compensated for in the dosimetry. Tumours have been treated both in experimental studies and in patients with thick superficial Basal Cell Carcinomas. Almost all treated skin lesions responded with complete response.
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Bendsöe, NielsLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)derm-nbe
(författare)
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Johansson, ThomasLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)fysi-tjo
(författare)
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Pålsson, SaraLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)fysi-spa
(författare)
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Soto Thompson, MarceloLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)fysi-mso
(författare)
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Stenram, UnneLund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pat-ust
(författare)
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Svanberg, KatarinaLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH,Tumörmikromiljö,Institutionen för kliniska vetenskaper, Lund,Tumor microenvironment,Department of Clinical Sciences, Lund(Swepub:lu)onk-ksv
(författare)
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Svanberg, SuneLund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)fysi-ssv
(författare)
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AtomfysikFysiska institutionen
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Advanced Optical Devices, Technologies, and Medical Applications: SPIE5123, s. 293-3020277-786X1996-756X
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Ingår i:Proceedings of SPIE: SPIE5123, s. 293-302
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