Changes in f-wave characteristics during cryoballoon catheter ablation

Henriksson, MikaelLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH (author)

OBJECTIVE: Changes in ECG-derived parameters are studied in atrial fibrillation (AF) patients undergoing cryoballoon catheter ablation.APPROACH: Parameters characterizing f-wave frequency, morphology by phase dispersion, and amplitude are estimated using a model-based statistical approach. These parameters are studied before, during, and after ablation, as well as for AF type (paroxysmal/persistent). Seventy-seven (49/28 paroxysmal/persistent) AF patients undergoing de novo catheter ablation are included in the study, out of which 31 (16/15 paroxysmal/persistent) were in AF during the whole procedure. A signal quality index (SQI) is used to identify analyzable segments.MAIN RESULTS: f-wave frequency decreased significantly during ablation (p = 0.001), in particular after ablation of the inferior right pulmonary vein (p < 0.05). Frequency and phase dispersion differed significantly between paroxysmal and persistent AF (p = 0.001 and p < 0.05, respectively).SIGNIFICANCE: This study demonstrates that a decrease in f-wave frequency can be distinguished during catheter ablation. The use of an SQI ensures reliable analysis and produces results significantly different from those obtained without an SQI.

García-Alberola, ArcadiUniversity of Murcia (author)
Goya, RebecaRey Juan Carlos University (author)
Vadillo, AlbaRey Juan Carlos University (author)
Melgarejo-Meseguer, Francisco ManuelUniversity of Murcia (author)
Sandberg, FridaLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)es-fni (author)
Sörnmo, LeifLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)tde-lso (author)
Avdelningen för Biomedicinsk teknikInstitutionen för biomedicinsk teknik (creator_code:org_t)

By the author/editor: Henriksson, Mika ...; García-Alberola, ...; Goya, Rebeca; Vadillo, Alba; Melgarejo-Mesegu ...; Sandberg, Frida; show more...; Sörnmo, Leif; show less...

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ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Laborato ...

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