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Diverse variola vir...
Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age
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- Mühlemann, Barbara (author)
- University of Cambridge,German Center for Infection Research (DZIF),Charité - University Medicine Berlin
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- Vinner, Lasse (author)
- University of Copenhagen
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- Margaryan, Ashot (author)
- Institute of Molecular Biology, National Academy of Sciences of Armenia,University of Copenhagen
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- Wilhelmson, Helene (author)
- Lund University,Lunds universitet,Gravarkeologiska forskargruppen – Död, begravning och social identitet,Forskargrupper vid Lunds universitet,Arkeologi,Institutionen för arkeologi och antikens historia,Institutioner,Humanistiska och teologiska fakulteterna,The Burial Archaeological Research Group – Death, Burial, and Social Identity,Lund University Research Groups,Archaeology,Department of Archaeology and Ancient History,Departments,Joint Faculties of Humanities and Theology
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- de la Fuente Castro, Constanza (author)
- University of Chicago
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- Allentoft, Morten E. (author)
- Curtin University,University of Copenhagen
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- de Barros Damgaard, Peter (author)
- University of Copenhagen
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- Hansen, Anders Johannes (author)
- University of Copenhagen
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- Holtsmark Nielsen, Sofie (author)
- University of Copenhagen
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- Strand, Lisa Mariann (author)
- Norwegian University of Science and Technology
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- Bill, Jan (author)
- University of Oslo
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- Buzhilova, Alexandra (author)
- Lomonosov Moscow State University
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- Pushkina, Tamara (author)
- Lomonosov Moscow State University
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- Falys, Ceri (author)
- Thames Valley Archaeological Services
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- Khartanovich, Valeri (author)
- Peter the Great Museum of Anthropology and Ethnography
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- Moiseyev, Vyacheslav (author)
- Peter the Great Museum of Anthropology and Ethnography
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- Jørkov, Marie Louise Schjellerup (author)
- University of Copenhagen
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- Østergaard Sørensen, Palle (author)
- Roskilde Museum,Frederikssund Museum
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- Magnusson, Yvonne (author)
- Malmö museer
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- Gustin, Ingrid (author)
- Lund University,Lunds universitet,Gravarkeologiska forskargruppen – Död, begravning och social identitet,Forskargrupper vid Lunds universitet,Historisk arkeologi,Institutionen för arkeologi och antikens historia,Institutioner,Humanistiska och teologiska fakulteterna,The Burial Archaeological Research Group – Death, Burial, and Social Identity,Lund University Research Groups,Historical Archaeology,Department of Archaeology and Ancient History,Departments,Joint Faculties of Humanities and Theology
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- Schroeder, Hannes (author)
- University of Copenhagen
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- Sutter, Gerd (author)
- Ludwig-Maximilian University of Munich,German Center for Infection Research (DZIF)
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- Smith, Geoffrey L. (author)
- University of Cambridge
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- Drosten, Christian (author)
- Charité - University Medicine Berlin,German Center for Infection Research (DZIF)
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- Fouchier, Ron A.M. (author)
- Erasmus University Medical Center
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- Smith, Derek J. (author)
- University of Cambridge
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- Willerslev, Eske (author)
- University of Cambridge,University of Southern Denmark,Wellcome Trust Sanger Institute,University of Copenhagen
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- Jones, Terry C. (author)
- Charité - University Medicine Berlin,German Center for Infection Research (DZIF),University of Cambridge
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- Sikora, Martin (author)
- University of Copenhagen
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(creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2020
- 2020
- English.
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In: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 369:6502
- Related links:
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http://dx.doi.org/10...
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https://www.duo.uio....
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Smallpox, one of the most devastating human diseases, killed between 300 million and 500 million people in the 20th century alone. We recovered viral sequences from 13 northern European individuals, including 11 dated to ~600-1050 CE, overlapping the Viking Age, and reconstructed near-complete variola virus genomes for four of them. The samples predate the earliest confirmed smallpox cases by ~1000 years, and the sequences reveal a now-extinct sister clade of the modern variola viruses that were in circulation before the eradication of smallpox. We date the most recent common ancestor of variola virus to ~1700 years ago. Distinct patterns of gene inactivation in the four near-complete sequences show that different evolutionary paths of genotypic host adaptation resulted in variola viruses that circulated widely among humans.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- HUMANIORA -- Historia och arkeologi -- Arkeologi (hsv//swe)
- HUMANITIES -- History and Archaeology -- Archaeology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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Mühlemann, Barba ...
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Vinner, Lasse
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Margaryan, Ashot
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Wilhelmson, Hele ...
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de la Fuente Cas ...
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Allentoft, Morte ...
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de Barros Damgaa ...
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Hansen, Anders J ...
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Holtsmark Nielse ...
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Strand, Lisa Mar ...
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Bill, Jan
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Buzhilova, Alexa ...
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Pushkina, Tamara
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Falys, Ceri
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Khartanovich, Va ...
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Moiseyev, Vyache ...
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Jørkov, Marie Lo ...
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Østergaard Søren ...
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Magnusson, Yvonn ...
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Gustin, Ingrid
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Schroeder, Hanne ...
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Sutter, Gerd
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Smith, Geoffrey ...
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Drosten, Christi ...
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Fouchier, Ron A. ...
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Smith, Derek J.
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Willerslev, Eske
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Jones, Terry C.
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Sikora, Martin
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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HUMANITIES
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and History and Arch ...
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and Archaeology
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Lund University