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Efficacy, immunogen...
Efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases : A systematic literature review for the 2019 update of EULAR recommendations
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- Rondaan, Christien (författare)
- University Medical Center Groningen
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- Furer, Victoria (författare)
- Tel-Aviv University,Tel Aviv Sourasky Medical Center – Ichilov Hospital
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- Heijstek, Marloes W. (författare)
- University Medical Center Utrecht
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- Agmon-Levin, Nancy (författare)
- Sheba Medical Center,Tel-Aviv University
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- Bijl, Marc (författare)
- Martini Hospital, Groningen
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- Breedveld, Ferdinand C. (författare)
- Leiden University Medical Centre
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- D'Amelio, Raffaele (författare)
- Sapienza University of Rome
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- Dougados, Maxime (författare)
- Paris Descartes University,Cochin Hospital
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- Kapetanovic, Meliha C. (författare)
- Lund University,Lunds universitet,Lund Arthritis Research Group (LARG),Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Van Laar, Jacob M. (författare)
- University Medical Center Utrecht
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- De Thurah, Annette Ladefoged (författare)
- Aarhus University Hospital
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- Landewé, Robert (författare)
- Zuyderland Medical Centre,Academic Medical Center of University of Amsterdam (AMC)
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- Molto, Anna (författare)
- Paris Descartes University,Cochin Hospital
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- Müller-Ladner, Ulf (författare)
- Justus Liebig University Giessen
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- Schreiber, Karen (författare)
- Guy's and St Thomas' NHS Foundation Trust,King Christian the Xth Hospital
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- Smolar, Leo (författare)
- No affiliation available (private)
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- Walker, Jim (författare)
- No affiliation available (private)
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- Warnatz, Klaus (författare)
- University Medical Center Freiburg
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- Wulffraat, Nico M. (författare)
- Wilhelmina Children’s Hospital
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- Van Assen, Sander (författare)
- Treant Zorggroep
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- Elkayam, Ori (författare)
- Tel Aviv Sourasky Medical Center – Ichilov Hospital,Tel-Aviv University
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(creator_code:org_t)
- 2019-09-09
- 2019
- Engelska.
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Ingår i: RMD Open. - : BMJ. - 2056-5933. ; 5:2
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://rmdopen.bmj....
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Aim To present a systematic literature review (SLR) on efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD), aiming to provide a basis for updating the EULAR evidence-based recommendations. Methods An SLR was performed according to the standard operating procedures for EULAR-endorsed recommendations. Outcome was determined by efficacy, immunogenicity and safety of vaccination in adult patients with AIIRD, including those receiving immunomodulating therapy. Furthermore, a search was performed on the effect of vaccinating household members of patients with AIIRD on the occurrence of vaccine-preventable infections in patients and their household members (including newborns). The literature search was performed using Medline, Embase and the Cochrane Library (October 2009 to August 2018). Results While most investigated vaccines were efficacious and/or immunogenic in patients with AIIRD, some were less efficacious than in healthy control subjects, and/or in patients receiving immunosuppressive agents. Adverse events of vaccination were generally mild and the rates were comparable to those in healthy persons. Vaccination did not seem to lead to an increase in activity of the underlying AIIRD, but insufficient power of most studies precluded arriving at definite conclusions. The number of studies investigating clinical efficacy of vaccination is still limited. No studies on the effect of vaccinating household members of patients with AIIRD were retrieved. Conclusion Evidence on efficacy, immunogenicity and safety of vaccination in patients with AIIRD was systematically reviewed to provide a basis for updated recommendations.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- autoimmune diseases
- infections
- vaccination
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Rondaan, Christi ...
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Furer, Victoria
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Heijstek, Marloe ...
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Agmon-Levin, Nan ...
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Bijl, Marc
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Breedveld, Ferdi ...
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D'Amelio, Raffae ...
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Dougados, Maxime
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Kapetanovic, Mel ...
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Van Laar, Jacob ...
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De Thurah, Annet ...
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Landewé, Robert
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Molto, Anna
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Müller-Ladner, U ...
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Schreiber, Karen
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Smolar, Leo
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Walker, Jim
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Warnatz, Klaus
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Wulffraat, Nico ...
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Van Assen, Sande ...
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Elkayam, Ori
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