Search: WFRF:(Mellqvist Ulf Henrik) >
Incidence, characte...
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Nahi, HarethKarolinska Institutet,Karolinska Institute,Karolinska Institute, Sweden,Karolinska Inst, Hematol, Stockholm, Sweden.
(author)
Incidence, characteristics, and outcome of solitary plasmacytoma and plasma cell leukemia. Population-based data from the Swedish Myeloma Register
- Article/chapterEnglish2017
Publisher, publication year, extent ...
Numbers
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LIBRIS-ID:oai:lup.lub.lu.se:47144aa0-dc6d-4f4b-8197-d284805ae2f1
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https://lup.lub.lu.se/record/47144aa0-dc6d-4f4b-8197-d284805ae2f1URI
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https://doi.org/10.1111/ejh.12907DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:136415143URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-140792URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-333951URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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Funding Agencies|Cancerfonden
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Solitary plasmacytoma (SP) and plasma cell leukemia (PCL) are uncommon (3-6%) types of plasma cell disease. The risk of progression to symptomatic multiple myeloma (MM) is probably important for the outcome of SP. PCL is rare and has a dismal outcome. In this study, we report on incidence and survival in PCL/SP, and progression to MM in SP, using the prospective observational Swedish Multiple Myeloma Register designed to document all newly diagnosed plasma cell diseases in Sweden since 2008. Both solitary bone plasmacytoma (SBP) (n=124) and extramedullary plasmacytoma (EMP) (n=67) have better overall survival (OS) than MM (n=3549). Progression to MM was higher in SBP than in EMP (35% and 7% at 2 years, respectively), but this did not translate into better survival in EMP. In spite of treatment developments, the OS of primary PCL is still dismal (median of 11 months, 0% at 5 years). Hence, there is a great need for diagnostic and treatment guidelines as well as prospective studies addressing the role for alternative treatment options, such as allogeneic stem cell transplantation and monoclonal antibodies in the treatment of PCL.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Genell, AnnaRegional Cancer Center Western Sweden,Regional Cancer Centre West, Sweden,Reg Canc Ctr West, Gothenburg, Sweden.
(author)
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Wålinder, GöranKarolinska Institutet,Karolinska Institute,Karolinska Institute, Sweden,Karolinska Inst, Hematol, Stockholm, Sweden.
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Uttervall, KatarinaKarolinska Institute,Karolinska Institute, Sweden,Karolinska Inst, Hematol, Stockholm, Sweden.
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Juliusson, GunnarLund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine,Lund University, Sweden,Lund Univ, Hematol, Lund, Sweden.(Swepub:lu)stem-gju
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Karin, ForsbergUmeå University,Umeå University Hospital, Sweden,Umea Univ Hosp, Hematol, Umea, Sweden.
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Hansson, MarkusLund University,Lunds universitet,Avdelningen för hematologi och transfusionsmedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Hematology and Transfusion Medicine,Department of Laboratory Medicine,Faculty of Medicine,Lund University, Sweden,Lund Univ, Hematol, Lund, Sweden.(Swepub:lu)hema-mha
(author)
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Svensson, RonaldLinköpings universitet,Institutionen för medicin och hälsa,Medicinska fakulteten,Region Östergötland, Hematologiska kliniken US,Linkoping Univ Hosp, Hematol, Linkoping, Sweden.(Swepub:liu)ronsv17
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Linder, OlleÖrebro University Hospital, Sweden,Orebro Univ Hosp, Hematol, Orebro, Sweden.
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Carlson, KristinaUppsala universitet,Hematologi(Swepub:uu)krica965
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Björkstrand, BoKarolinska Institute,Karolinska Institute, Sweden,Karolinska Inst, Hematol, Stockholm, Sweden.
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Kristinsson, Sigurdur YKarolinska Institute,Karolinska Institute, Sweden,Karolinska Inst, Hematol, Stockholm, Sweden.
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Mellqvist, Ulf-HenrikSouth Elvsborg Hospital, Sweden,South Elvsborg Hosp, Hematol, Boras, Sweden.
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Blimark, CecilieSahlgrens University Hospital, Sweden,Sahlgrens Univ Hosp, Hematol, Gothenburg, Sweden.
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Turesson, IngemarSkåne University Hospital, Sweden,Skane Univ Hosp, Hematol, Malmo, Sweden.(Swepub:lu)medf-itu
(author)
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Karolinska InstitutetKarolinska Institute
(creator_code:org_t)
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In:European Journal of Haematology: Wiley99:3, s. 216-2220902-44411600-0609
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Nahi, Hareth
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Genell, Anna
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Wålinder, Göran
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Uttervall, Katar ...
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Juliusson, Gunna ...
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Karin, Forsberg
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Hansson, Markus
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Svensson, Ronald
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Linder, Olle
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Carlson, Kristin ...
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Björkstrand, Bo
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Kristinsson, Sig ...
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Mellqvist, Ulf-H ...
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Blimark, Cecilie
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Turesson, Ingema ...
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