Association between sickle cell trait and the prevalence and severity of diabetic retinopathy

Purpose To determine whether Sickle cell trait (SCT) is associated with an increased severity of diabetic retinopathy. Methods This was a single center retrospective study case control study of 100 eyes of 100 patients with diabetes mellitus (DM) with SCT (SCT group) and 100 eyes of 100 age-matched patients with DM without SCT (control group). The main outcome measure was the difference in the prevalence of sight threatening DR [here defined as diabetic macular edema (DME) and/or proliferative diabetic retinopathy (PDR)], between the SCT and control groups. Secondary outcome measures included differences in visual acuity, ocular comorbidities, intraocular pressure, glycemic control as assessed by random blood glucose measurement, diabetes duration, nephropathy, hyperlipidemia and hypertension. Results The SCT group had statistically significantly shorter duration of DM (median [25% quartile] 15 [8.3] years versus 20 [14.7] years, respectively)(P

Khandekar, RajivKing Khaled Eye Specialist Hospital (författare)
Kozak, IgorKing Khaled Eye Specialist Hospital (författare)
Schatz, PatrikLund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,King Khaled Eye Specialist Hospital(Swepub:lu)oft-psc (författare)
King Khaled Eye Specialist HospitalOftalmologi, Lund (creator_code:org_t)

Av författaren/redakt...: Harbi, Majed Al; Khandekar, Rajiv; Kozak, Igor; Schatz, Patrik

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Oftalmologi

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