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Sökning: id:"swepub:oai:lup.lub.lu.se:4735da85-579f-484b-b374-3fe45c77a1ee" > Distal radius fract...

  • Baruth, Joshua M.Mayo Clinic Minnesota (författare)

Distal radius fractures and risk of incident neurocognitive disorders in older adults : a retrospective cohort study

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • 2022-07-15
  • Springer Science and Business Media LLC,2022

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:4735da85-579f-484b-b374-3fe45c77a1ee
  • https://lup.lub.lu.se/record/4735da85-579f-484b-b374-3fe45c77a1eeURI
  • https://doi.org/10.1007/s00198-022-06497-6DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Introduction: Distal radius fractures (DRF) are associated with increased risk of subsequent fractures and physical decline in older adults. This study aims to evaluate the risk cognitive decline following DRF and potential for timely screening and intervention. Methods: A cohort of 1046 individuals 50–75 years of age with DRF were identified between 1995 and 2015 (81.5% female; mean age 62.5 [± 7.1] years). A control group (N = 1044) without history of DRF was matched by age, sex, and fracture date (i.e., index). The incidence of neurocognitive disorders (NCD) in relation to DRF/index was determined. Group comparisons were adjusted by age and comorbidity measured by the Elixhauser index. Results: The DRF group had a greater incidence of NCD compared to the control group (11.3% vs. 8.2%) with a 56% greater relative risk (HR = 1.56, 95% Cl: 1.18, 2.07; p = 0.002) after adjusting for age and comorbidity. For every 10-year age increase, the DRF group was over three times more likely to develop a NCD (HR = 3.23, 95% Cl: 2.57, 4.04; p < 0.001). Conclusion: DRF in adults ages 50 to 75 are associated with increased risk of developing neurocognitive disorders. DRF may represent a sentinel opportunity for cognitive screening and early intervention. Summary: Distal radius fractures (DRF) have been associated with greater risk of future fractures and physical decline. This study reports that DRF are also associated with greater risk of developing neurocognitive disorders in older adults. Timely intervention may improve early recognition and long-term outcomes for older adults at risk of cognitive decline.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Lapid, Maria I.Mayo Clinic Minnesota (författare)
  • Clarke, BartMayo Clinic Minnesota (författare)
  • Shin, Alexander Y.Mayo Clinic Minnesota (författare)
  • Atkinson, Elizabeth J.Mayo Clinic Minnesota (författare)
  • Eberhard, JonasLund University,Lunds universitet,Forskningsenheten: svårbehandlade psykiatriska tillstånd,Forskargrupper vid Lunds universitet,Severe Mental Illness research unit,Lund University Research Groups(Swepub:lu)psyk-jeb (författare)
  • Zavatta, GuidoUniversity of Bologna (författare)
  • Åstrand, JörgenLund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)ort-jas (författare)
  • Mayo Clinic MinnesotaForskningsenheten: svårbehandlade psykiatriska tillstånd (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Osteoporosis International: Springer Science and Business Media LLC33:11, s. 2307-23140937-941X1433-2965

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