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- Dunér, PontusLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups (author)
Increased aldehyde-modification of collagen type IV in symptomatic plaques - A possible cause of endothelial dysfunction.
- Article/chapterEnglish2015
Publisher, publication year, extent ...
- Elsevier BV,2015
- electronicrdacarrier
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- LIBRIS-ID:oai:lup.lub.lu.se:49827797-6a2c-4eb2-8774-7271aca7edc3
- https://lup.lub.lu.se/record/5265128URI
- https://doi.org/10.1016/j.atherosclerosis.2015.02.043DOI
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- Language:English
- Summary in:English
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- Subendothelial LDL-adhesion and its subsequent oxidation are considered as key events in the development of atherosclerotic lesions. During oxidation of LDL, reactive aldehydes such as malondialdehyde (MDA) are formed, which modify apolipoprotein B100. However, the possibility that these reactive aldehydes could leak out of the LDL-particle and modify surrounding extracellular matrix proteins has been largely unexplored. We have investigated if aldehyde-modification of collagen type IV, one of the major basement membrane components, in plaques is associated with cardiovascular events.
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- Goncalves, IsabelLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Kardiovaskulär forskning - translationella studier,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups,Cardiovascular Research - Translational Studies(Swepub:lu)medf-igo (author)
- Grufman, HelenaLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)med-hgm (author)
- Edsfeldt, AndreasLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)med-aet (author)
- To, FongLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)medf-fto (author)
- Nitulescu, MihaelaLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)medf-mni (author)
- Nilsson, JanLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)medf-jni (author)
- Bengtsson, EvaLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)medf-eb0 (author)
- Kardiovaskulär forskning - immunitet och aterosklerosForskargrupper vid Lunds universitet (creator_code:org_t)
Related titles
- In:Atherosclerosis: Elsevier BV240:1, s. 26-321879-14840021-9150
Internet link
- https://portal.research.lu.se/files/1819080/8056711.pdfFULLTEXT
- http://www.ncbi.nlm.nih.gov/pubmed/25746374?dopt=AbstractFULLTEXT
- http://dx.doi.org/10.1016/j.atherosclerosis.2015.02.043FULLTEXT
- https://lup.lub.lu.se/search/files/1819080/8056711.pdf
- https://lup.lub.lu.se/record/5265128
- https://doi.org/10.1016/j.atherosclerosis.2015.02.043
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