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A randomised contro...
A randomised controlled trial of integrated psychological therapy for traumatic stress and substance use among adolescents: Trial protocol
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- Mills, Katherine (author)
- University of Sydney
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- Barrett, Emma (author)
- University of Sydney
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- Back, Sudie (author)
- Medical University of South Carolina
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- Cobham, Vanessa (author)
- University of Queensland
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- Bendall, Sarah (author)
- Orygen - National Centre for Excellence in Youth Mental Health
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- Perrin, Sean (author)
- Lund University,Lunds universitet,Institutionen för psykologi,Samhällsvetenskapliga institutioner och centrumbildningar,Samhällsvetenskapliga fakulteten,Department of Psychology,Departments of Administrative, Economic and Social Sciences,Faculty of Social Sciences
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- Brady, Kathleen (author)
- Medical University of South Carolina
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- Ross, Joanne (author)
- National Drug & Alcohol Research Centre,University of New South Wales
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- Peach, Natalie (author)
- University of Sydney
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- Kihas, Ivana (author)
- University of Sydney
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- Cassar, Joanne (author)
- University of Sydney
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- Schollar-Root, Olivia (author)
- University of Sydney
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- Teesson, Maree (author)
- University of Sydney
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(creator_code:org_t)
- 2020-11-30
- 2020
- English.
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In: BMJ Open. - : BMJ. - 2044-6055. ; 10
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Abstract
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- Introduction: Post-traumatic stress disorder (PTSD) and substance use disorder frequently co-occur and tend to have their onset during adolescence. Although research has highlighted the importance of treating these disorders in an integrated fashion, there is a dearth of empirically validated integrated treatment options for adolescents with this comorbidity. This paper describes the study protocol for a randomised controlled trial (RCT) examining the efficacy of an integrated trauma-focused cognitive–behavioural treatment for traumatic stress and substance use among adolescents (Concurrent Treatment of PTSD and Substance Use Using Prolonged Exposure - Adolescent (COPE-A)), relative to a supportive counselling control condition (Person-Centred Therapy (PCT)). Methods and analysis: A two-arm, parallel, single-blind RCT with blinded follow-up at 4 and 12 months poststudy entry will be conducted in Sydney, Australia. Participants (n~100 adolescents aged 12–18 years) and their caregivers (caregiver participation is optional) will be allocated to undergo either COPE-A or PCT (allocation ratio 1:1) using minimisation. Both therapies will be delivered individually by project psychologists over a maximum of 16 sessions of 60–90 min duration and will include provision of up to four 30 min optional caregiver sessions. The primary outcome will be between-group differences in change in the severity of PTSD symptoms from baseline to 4-month follow-up, as measured by the Clinician-Administered PTSD Scale for Children and Adolescents for DSM-5. Ethics and dissemination: Ethical approval has been obtained from the human research ethics committees of the Sydney Children’s Hospital Network (HREC/17/SCHN/306) and the University of Sydney (HREC 2018/863). Findings will be published in peer-reviewed journals and presented at scientific conferences. Trial registration number: ACTRN12618000785202; Pre-reults.
Subject headings
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- PTSD
- Substance use disorders
- Children and Adolescents
- Randomized Controlled Trial
- CBT
- Integrated Treatment
Publication and Content Type
- art (subject category)
- ref (subject category)
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BMJ Open
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- By the author/editor
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Mills, Katherine
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Barrett, Emma
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Back, Sudie
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Cobham, Vanessa
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Bendall, Sarah
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Perrin, Sean
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show more...
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Brady, Kathleen
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Ross, Joanne
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Peach, Natalie
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Kihas, Ivana
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Cassar, Joanne
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Schollar-Root, O ...
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Teesson, Maree
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- About the subject
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
- Articles in the publication
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BMJ Open
- By the university
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Lund University