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  • Emery, Carolyn AUniversity of Calgary (author)

Establishing outcome measures in early knee osteoarthritis

  • Article/chapterEnglish2019

Publisher, publication year, extent ...

  • 2019-06-14
  • Springer Science and Business Media LLC,2019

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:51b51937-f700-48f4-8679-2c35bca003aa
  • https://lup.lub.lu.se/record/51b51937-f700-48f4-8679-2c35bca003aaURI
  • https://doi.org/10.1038/s41584-019-0237-3DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:for swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • The classification and monitoring of individuals with early knee osteoarthritis (OA) are important considerations for the design and evaluation of therapeutic interventions and require the identification of appropriate outcome measures. Potential outcome domains to assess for early OA include patient-reported outcomes (such as pain, function and quality of life), features of clinical examination (such as joint line tenderness and crepitus), objective measures of physical function, levels of physical activity, features of imaging modalities (such as of magnetic resonance imaging) and biochemical markers in body fluid. Patient characteristics such as adiposity and biomechanics of the knee could also have relevance to the assessment of early OA. Importantly, research is needed to enable the selection of outcome measures that are feasible, reliable and validated in individuals at risk of knee OA or with early knee OA. In this Perspectives article, potential outcome measures for early symptomatic knee OA are discussed, including those measures that could be of use in clinical practice and/or the research setting.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Whittaker, Jackie LUniversity of Alberta (author)
  • Mahmoudian, ArmaghanUniversity Hospitals Leuven (author)
  • Lohmander, L StefanLund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Nedbrytning av ledbrosk: en biologisk process som leder till artros,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund OsteoArthritis Division - Molecular marker research group,Lund University Research Groups,Skåne University Hospital(Swepub:lu)ort-slo (author)
  • Roos, Ewa MUniversity of Southern Denmark(Swepub:lu)ort-ero (author)
  • Bennell, Kim LUniversity of Melbourne (author)
  • Toomey, Clodagh MUniversity of Calgary (author)
  • Reimer, Raylene AUniversity of Calgary (author)
  • Thompson, DylanUniversity of Bath (author)
  • Ronsky, Janet LUniversity of Calgary (author)
  • Kuntze, GregorUniversity of Calgary (author)
  • Lloyd, David GGriffith University (author)
  • Andriacchi, ThomasVA Palo Alto Health Care System (author)
  • Englund, MartinLund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Clinical Epidemiology Unit,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups(Swepub:lu)ort-med (author)
  • Kraus, Virginia BDuke University (author)
  • Losina, ElenaBoston University,Brigham and Women's Hospital / Harvard Medical School,Harvard University (author)
  • Bierma-Zeinstra, SitaErasmus University Medical Center (author)
  • Runhaar, JosErasmus University Medical Center (author)
  • Peat, GeorgeKeele University (author)
  • Luyten, Frank PUniversity Hospitals Leuven (author)
  • Snyder-Mackler, LynnUniversity of Delaware (author)
  • Risberg, May ArnaOslo university hospital (author)
  • Mobasheri, AliQueen's Medical Centre, Nottingham (author)
  • Guermazi, AliBoston University (author)
  • Hunter, David JUniversity of Sydney,Royal North Shore Hospital (author)
  • Arden, Nigel KOxford Brookes University (author)
  • University of CalgaryUniversity of Alberta (creator_code:org_t)

Related titles

  • In:Nature Reviews Rheumatology: Springer Science and Business Media LLC15:7, s. 438-4481759-48041759-4790

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