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A scoping review of...
A scoping review of how early-stage knee osteoarthritis has been defined
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- Liew, Jean W (författare)
- Boston University
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- King, Lauren K (författare)
- University of Toronto
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- Mahmoudian, Armaghan (författare)
- Lund University,Lunds universitet,Lund OsteoArthritis Division - Clinical Epidemiology Unit,Forskargrupper vid Lunds universitet,Lund University Research Groups
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- Wang, Qiuke (författare)
- Erasmus University Medical Center
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- Atkinson, Hayden F (författare)
- University of Western Ontario
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- Flynn, David B (författare)
- Boston University
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- Appleton, C Thomas (författare)
- University of Western Ontario
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- Englund, Martin (författare)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Clinical Epidemiology Unit,Forskargrupper vid Lunds universitet,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,LU Profile Area: Proactive Ageing,Lund University Profile areas
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Haugen, Ida K (författare)
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- Lohmander, L Stefan (författare)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Nedbrytning av ledbrosk: en biologisk process som leder till artros,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund OsteoArthritis Division - Molecular marker research group,Lund University Research Groups
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- Runhaar, Jos (författare)
- Erasmus University Medical Center
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- Neogi, Tuhina (författare)
- Boston University
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- Hawker, Gillian (författare)
- University of Toronto
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(creator_code:org_t)
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- 2023
- 2023
- Engelska.
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Ingår i: Osteoarthritis and Cartilage. - 1063-4584. ; 31:9, s. 1234-1241
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Early-stage knee osteoarthritis (KOA) classification criteria will enable consistent identification and trial recruitment of individuals with knee osteoarthritis (OA) at an earlier stage of the disease when interventions may be more effective. Toward this goal, we identified how early-stage KOA has been defined in the literature.METHODS: We performed a scoping literature review in PubMed, EMBASE, Cochrane, and Web of Science, including human studies where early-stage KOA was included as a study population or outcome. Extracted data included demographics, symptoms/history, examination, laboratory, imaging, performance-based measures, gross inspection/histopathologic domains, and the components of composite early-stage KOA definitions.RESULTS: Of 6142 articles identified, 211 were included in data synthesis. An early-stage KOA definition was used for study inclusion in 194 studies, to define study outcomes in 11 studies, and in the context of new criteria development or validation in six studies. The element most often used to define early-stage KOA was Kellgren-Lawrence (KL) grade (151 studies, 72%), followed by symptoms (118 studies, 56%), and demographic characteristics (73 studies, 35%); 14 studies (6%) used previously developed early-stage KOA composite criteria. Among studies defining early-stage KOA radiographically, 52 studies defined early-stage KOA by KL grade alone; of these 52, 44 (85%) studies included individuals with KL grade 2 or higher in their definitions.CONCLUSION: Early-stage KOA is variably defined in the published literature. Most studies included KL grades of 2 or higher within their definitions, which reflects established or later-stage OA. These findings underscore the need to develop and validate classification criteria for early-stage KOA.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Nyckelord
- Humans
- Osteoarthritis, Knee/diagnostic imaging
- Knee Joint/pathology
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Till lärosätets databas
- Av författaren/redakt...
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Liew, Jean W
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King, Lauren K
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Mahmoudian, Arma ...
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Wang, Qiuke
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Atkinson, Hayden ...
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Flynn, David B
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visa fler...
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Appleton, C Thom ...
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Englund, Martin
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Haugen, Ida K
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Lohmander, L Ste ...
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Runhaar, Jos
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Neogi, Tuhina
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Hawker, Gillian
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Ortopedi
- Artiklar i publikationen
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Osteoarthritis a ...
- Av lärosätet
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Lunds universitet