Scatterer size estimation using the center frequency assessed from ultrasound time domain data

Erlöv, TobiasLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH (author)

Scatterer size estimation is useful when characterizing tissue using ultrasound. In all previous studies on scatterer size, the estimations are performed in the frequency domain and are thus subjected to a trade off in time-frequency resolution. This study focused on the feasibility of estimating scatterer size in the time domain using only the ultrasound center frequency, assuming a Gaussian-shaped pulse. A model for frequency normalization was derived and the frequency-dependent attenuation was compensated. Five phantoms with well-defined sizes of spherical glass beads were made and scanned with two different linear array transducers with variable center frequencies. A strong correlation (r = 0.99, p < 10-19) between the backscattered center frequency and the product between the wave number and scatterer radius was demonstrated. On average the scatterer diameter was underestimated by 6% ± 24%. These results suggest that estimation of scatterer size is possible using only the center frequency assessed in the time domain.

Jansson, TomasLund University,Lunds universitet,Medicinskt ultraljud,Forskargrupper vid Lunds universitet,Medical ultrasound,Lund University Research Groups,Skåne University Hospital(Swepub:lu)elma-tja (author)
Persson, Hans W.Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)elma-hpe (author)
Cinthio, MagnusLund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)elma-mpe (author)
Avdelningen för Biomedicinsk teknikInstitutionen för biomedicinsk teknik (creator_code:org_t)

In:Journal of the Acoustical Society of America: Acoustical Society of America (ASA)140:4, s. 2352-23570001-4966

By the author/editor: Erlöv, Tobias; Jansson, Tomas; Persson, Hans W.; Cinthio, Magnus

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