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Dietary vitamin D i...
Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study
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Abbas, S. (author)
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Linseisen, J. (author)
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Rohrmann, S. (author)
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show more...
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Beulens, J. W. J. (author)
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Buijsse, B. (author)
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Amiano, P. (author)
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Ardanaz, E. (author)
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Balkau, B. (author)
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Boeing, H. (author)
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Clavel-Chapelon, F. (author)
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Fagherazzi, G. (author)
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- Franks, Paul (author)
- Umeå universitet,Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Medicin
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Gavrila, D. (author)
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Grioni, S. (author)
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Kaaks, R. (author)
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Key, T. J. (author)
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Khaw, K. T. (author)
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Kuehn, T. (author)
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Mattiello, A. (author)
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Molina-Montes, E. (author)
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Nilsson, P. M. (author)
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Overvad, K. (author)
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Quiros, J. R. (author)
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- Rolandsson, Olov (author)
- Umeå universitet,Allmänmedicin
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Sacerdote, C. (author)
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Saieva, C. (author)
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Slimani, N. (author)
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Sluijs, I. (author)
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Spijkerman, A. M. W. (author)
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Tjonneland, A. (author)
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Tumino, R. (author)
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van der A, D. L. (author)
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Zamora-Ros, R. (author)
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Sharp, S. J. (author)
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Langenberg, C. (author)
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Forouhi, N. G. (author)
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Riboli, E. (author)
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Wareham, N. J. (author)
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(creator_code:org_t)
- 2013-11-20
- 2014
- English.
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In: European Journal of Clinical Nutrition. - : Springer Science and Business Media LLC. - 1476-5640 .- 0954-3007. ; 68:2, s. 196-202
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http://dx.doi.org/10...
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https://www.nature.c...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- BACKGROUND/OBJECTIVES: Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study in a heterogeneous European population including eight countries with large geographical variation. SUBJECTS/METHODS: Using a case-cohort design, 11 245 incident cases of type 2 diabetes and a representative subcohort (N = 15 798) were included in the analyses. Hazard ratios (HR) and 95% confidence intervals (CIs) for type 2 diabetes were calculated using a Prentice-weighted Cox regression adjusted for potential confounders. Twenty-four-hour diet-recall data from a subsample (N = 2347) were used to calibrate habitual intake data derived from dietary questionnaires. RESULTS: Median follow-up time was 10.8 years. Dietary vitamin D intake was not significantly associated with the risk of type 2 diabetes. HR and 95% CIs for the highest compared to the lowest quintile of uncalibrated vitamin D intake was 1.09 (0.97-1.22) (P-trend = 0.17). No associations were observed in a sex-specific analysis. The overall pooled effect (HR (95% CI)) using the continuous calibrated variable was 1.00 (0.97-1.03) per increase of 1 mg/day dietary vitamin D. CONCLUSIONS: This observational study does not support an association between higher dietary vitamin D intake and type 2 diabetes incidence. This result has to be interpreted in light of the limited contribution of dietary vitamin D on the overall vitamin D status of a person.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- vitamin D
- type 2 diabetes
- dietary intake
- observational study
- EPIC
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Abbas, S.
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Linseisen, J.
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Rohrmann, S.
-
Beulens, J. W. J ...
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Buijsse, B.
-
Amiano, P.
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show more...
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Ardanaz, E.
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Balkau, B.
-
Boeing, H.
-
Clavel-Chapelon, ...
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Fagherazzi, G.
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Franks, Paul
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Gavrila, D.
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Grioni, S.
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Kaaks, R.
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Key, T. J.
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Khaw, K. T.
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Kuehn, T.
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Mattiello, A.
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Molina-Montes, E ...
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Nilsson, P. M.
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Overvad, K.
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Quiros, J. R.
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Rolandsson, Olov
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Sacerdote, C.
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Saieva, C.
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Slimani, N.
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Sluijs, I.
-
Spijkerman, A. M ...
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Tjonneland, A.
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Tumino, R.
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van der A, D. L.
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Zamora-Ros, R.
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Sharp, S. J.
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Langenberg, C.
-
Forouhi, N. G.
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Riboli, E.
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Wareham, N. J.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nutrition and Di ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
- Articles in the publication
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European Journal ...
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Lund University
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Umeå University