WFRF:(Ruilope Luis Miguel)
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Blood pressure and low-density lipoprotein-cholesterol lowering for prevention of strokes and cognitive decline: a review of available trial evidence.
- Zanchetti, Alberto (author)
- Liu, Lisheng (author)
- Mancia, Giuseppe (author)
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- Parati, Gianfranco (author)
- Grassi, Guido (author)
- Stramba-Badiale, Marco (author)
- Silani, Vincenzo (author)
- Bilo, Grzegorz (author)
- Corrao, Giovanni (author)
- Zambon, Antonella (author)
- Scotti, Lorenza (author)
- Zhang, Xinhua (author)
- Wang, HayYan (author)
- Zhang, Yuqing (author)
- Zhang, Xuezhong (author)
- Guan, Ting Rui (author)
- Berge, Eivind (author)
- Redon, Josep (author)
- Narkiewicz, Krzysztof (author)
- Dominiczak, Anna (author)
- Viigimaa, Margus (author)
- Laurent, Stéphane (author)
- Agabiti-Rosei, Enrico (author)
- Wu, Zhaosu (author)
- Zhu, Dingliang (author)
- Rodicio, José Luis (author)
- Ruilope, Luis Miguel (author)
- Martell-Claros, Nieves (author)
- Pinto, Fernando (author)
- Schmieder, Roland E (author)
- Burnier, Michel (author)
- Banach, Maciej (author)
- Cifkova, Renata (author)
- Farsang, Csaba (author)
- Konradi, Alexandra (author)
- Lazareva, Irina (author)
- Sirenko, Yuriy (author)
- Dorobantu, Maria (author)
- Postadzhiyan, Arman (author)
- Accetto, Rok (author)
- Jelakovic, Bojan (author)
- Lovic, Dragan (author)
- Manolis, Athanasios J (author)
- Stylianou, Philippos (author)
- Erdine, Serap (author)
- Dicker, Dror (author)
- Wei, Gangzhi (author)
- Xu, Chengbin (author)
- Xie, Hengge (author)
- Coca, Antonio (author)
- O'Brien, John (author)
- Ford, Gary (author)
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- (creator_code:org_t)
- 2014
- 2014
- English.
- In: Journal of Hypertension. - 1473-5598. ; 32:9, s. 1741-1750
- Research review (peer-reviewed)
Abstract
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- It is well established by a large number of randomized controlled trials that lowering blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) by drugs are powerful means to reduce stroke incidence, but the optimal BP and LDL-C levels to be achieved are largely uncertain. Concerning BP targets, two hypotheses are being confronted: first, the lower the BP, the better the treatment outcome, and second, the hypothesis that too low BP values are accompanied by a lower benefit and even higher risk. It is also unknown whether BP lowering and LDL-C lowering have additive beneficial effects for the primary and secondary prevention of stroke, and whether these treatments can prevent cognitive decline after stroke.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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- Zanchetti, Alber ...
- Liu, Lisheng
- Mancia, Giuseppe
- Parati, Gianfran ...
- Grassi, Guido
- Stramba-Badiale, ...
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- Silani, Vincenzo
- Bilo, Grzegorz
- Corrao, Giovanni
- Zambon, Antonell ...
- Scotti, Lorenza
- Zhang, Xinhua
- Wang, HayYan
- Zhang, Yuqing
- Zhang, Xuezhong
- Guan, Ting Rui
- Berge, Eivind
- Redon, Josep
- Narkiewicz, Krzy ...
- Dominiczak, Anna
- Nilsson, Peter
- Viigimaa, Margus
- Laurent, Stéphan ...
- Agabiti-Rosei, E ...
- Wu, Zhaosu
- Zhu, Dingliang
- Rodicio, José Lu ...
- Ruilope, Luis Mi ...
- Martell-Claros, ...
- Pinto, Fernando
- Schmieder, Rolan ...
- Burnier, Michel
- Banach, Maciej
- Cifkova, Renata
- Farsang, Csaba
- Konradi, Alexand ...
- Lazareva, Irina
- Sirenko, Yuriy
- Dorobantu, Maria
- Postadzhiyan, Ar ...
- Accetto, Rok
- Jelakovic, Bojan
- Lovic, Dragan
- Manolis, Athanas ...
- Stylianou, Phili ...
- Erdine, Serap
- Dicker, Dror
- Wei, Gangzhi
- Xu, Chengbin
- Xie, Hengge
- Coca, Antonio
- O'Brien, John
- Ford, Gary
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- MEDICAL AND HEALTH SCIENCES
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