SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Marie Nathalie)
 

Search: WFRF:(Marie Nathalie) > (2010-2014) > Multiple Miscarriag...

  • Braem, Marieke G. M. (author)

Multiple Miscarriages Are Associated with the Risk of Ovarian Cancer: Results from the European Prospective Investigation into Cancer and Nutrition

  • Article/chapterEnglish2012

Publisher, publication year, extent ...

  • 2012-05-18
  • Public Library of Science (PLoS),2012
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:5e1ed54e-b06f-473b-a353-1d8ab5ce3e83
  • https://lup.lub.lu.se/record/2890710URI
  • https://doi.org/10.1371/journal.pone.0037141DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57379URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • While the risk of ovarian cancer clearly reduces with each full-term pregnancy, the effect of incomplete pregnancies is unclear. We investigated whether incomplete pregnancies (miscarriages and induced abortions) are associated with risk of epithelial ovarian cancer. This observational study was carried out in female participants of the European Prospective Investigation into Cancer and Nutrition (EPIC). A total of 274,442 women were followed from 1992 until 2010. The baseline questionnaire elicited information on miscarriages and induced abortions, reproductive history, and lifestyle-related factors. During a median follow-up of 11.5 years, 1,035 women were diagnosed with incident epithelial ovarian cancer. Despite the lack of an overall association (ever vs. never), risk of ovarian cancer was higher among women with multiple incomplete pregnancies (HR >= 4vs.0: 1.74, 95% CI: 1.20-2.70; number of cases in this category: n = 23). This association was particularly evident for multiple miscarriages (HR >= 4vs.0: 1.99, 95% CI: 1.06-3.73; number of cases in this category: n = 10), with no significant association for multiple induced abortions (HR >= 4vs.0: 1.46, 95% CI: 0.68-3.14; number of cases in this category: n = 7). Our findings suggest that multiple miscarriages are associated with an increased risk of epithelial ovarian cancer, possibly through a shared cluster of etiological factors or a common underlying pathology. These findings should be interpreted with caution as this is the first study to show this association and given the small number of cases in the highest exposure categories.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Onland-Moret, N. Charlotte (author)
  • Schouten, Leo J. (author)
  • Kruitwagen, Roy F. P. M. (author)
  • Lukanova, Annekatrin (author)
  • Allen, Naomi E. (author)
  • Wark, Petra A. (author)
  • Tjonneland, Anne (author)
  • Hansen, Louise (author)
  • Brauner, Christina Marie (author)
  • Overvad, Kim (author)
  • Clavel-Chapelon, Francoise (author)
  • Chabbert-Buffet, Nathalie (author)
  • Teucher, Birgit (author)
  • Floegel, Anna (author)
  • Boeing, Heiner (author)
  • Trichopoulou, Antonia (author)
  • Adarakis, George (author)
  • Plada, Maria (author)
  • Rinaldi, Sabina (author)
  • Fedirko, Veronika (author)
  • Romieu, Isabelle (author)
  • Pala, Valeria (author)
  • Galasso, Rocco (author)
  • Sacerdote, Carlotta (author)
  • Palli, Domenico (author)
  • Tumino, Rosario (author)
  • Bueno-de-Mesquita, H. Bas (author)
  • Gram, Inger Torhild (author)
  • Gavrilyuk, Oxana (author)
  • Lund, Eiliv (author)
  • Sanchez, Maria-Jose (author)
  • Bonet, Catalina (author)
  • Chirlaque, Maria-Dolores (author)
  • Larranaga, Nerea (author)
  • Barricarte Gurrea, Aurelio (author)
  • Quiros, Jose R. (author)
  • Idahl, AnnikaUmeå universitet,Obstetrik och gynekologi,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)anid0002 (author)
  • Ohlson, NinaUmeå universitet,Patologi(Swepub:umu)niaohn95 (author)
  • Lundin, EvaUmeå universitet,Patologi(Swepub:umu)evlu0001 (author)
  • Jirström, KarinLund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pat-kji (author)
  • Butt, SalmaLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups(Swepub:lu)med-smb (author)
  • Tsilidis, Konstantinos K. (author)
  • Khaw, Kay-Tee (author)
  • Wareham, Nick (author)
  • Riboli, Elio (author)
  • Kaaks, Rudolf (author)
  • Peeters, Petra H. M. (author)
  • Umeå universitetObstetrik och gynekologi (creator_code:org_t)

Related titles

  • In:PLoS ONE: Public Library of Science (PLoS)7:51932-6203

Internet link

Find in a library

  • PLoS ONE (Search for host publication in LIBRIS)

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view