Sökning: id:"swepub:oai:lup.lub.lu.se:5f2af8f4-d716-407b-b007-f709af73c73c" >
Lack of concealment...
Lack of concealment may lead to selection bias in cluster randomized trials of palliative care
- Artikel/kapitelEngelska2002
Förlag, utgivningsår, omfång ...
-
2016-07-01
-
SAGE Publications,2002
Nummerbeteckningar
-
LIBRIS-ID:oai:lup.lub.lu.se:5f2af8f4-d716-407b-b007-f709af73c73c
-
https://lup.lub.lu.se/record/893600URI
-
https://doi.org/10.1191/0269216302pm523oaDOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:art swepub-publicationtype
-
Ämneskategori:ref swepub-contenttype
Anmärkningar
-
Comprehensive palliative care programs are often implemented on a community level, and to evaluate such interventions, randomization by cluster (community) may be the only feasible method. In trials randomizing individual subjects, the importance of proper concealment has been stressed, In cluster randomized trials, however, concealment of individual patient allocation is often impossible. The following risk of selection bias has been given little attention. In the present study, comparing palliative care to conventional care, community health care districts were defined as clusters and randomized. The patients' treatment assignment was determined by the allocation of the cluster in which they resided, and hence predictable by their address. A biased selection based on practical considerations related to patients' diagnoses and hospital departments was suspected. To explore this, cancer diagnoses were grouped according to local tradition for sharing of treatment responsibility among hospital departments. A significant difference between trial arms in distribution of these groups was revealed and strongly supported our suspicion. The finding carries an important message to future researchers: when using cluster randomization, any evidence of selection bias should be carefully checked and reported.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Fayers, PM
(författare)
-
Ahlner-Elmqvist, MarianneLund University,Lunds universitet,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups(Swepub:lu)oron-mah
(författare)
-
Kaasa, S
(författare)
-
Laryngoesofagologi, allergi och livskvalitetForskargrupper vid Lunds universitet
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Palliative Medicine: SAGE Publications16:1, s. 43-491477-030X0269-2163
Internetlänk
Hitta via bibliotek
Till lärosätets databas