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Environmental DNA r...
Environmental DNA reveals links between abundance and composition of airborne grass pollen and respiratory health
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- Rowney, Francis M (author)
- University of Exeter
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- Brennan, Georgina L (author)
- Lund University,Lunds universitet,Centrum för miljö- och klimatvetenskap (CEC),Naturvetenskapliga fakulteten,Akvatisk ekologi,Forskargrupper vid Lunds universitet,Centre for Environmental and Climate Science (CEC),Faculty of Science,Aquatic Ecology,Lund University Research Groups,Bangor University
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- Skjøth, Carsten A (author)
- University of Worcester
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- Griffith, Gareth W (author)
- Aberystwyth University
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- McInnes, Rachel N (author)
- Met Office
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- Clewlow, Yolanda (author)
- Met Office
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- Adams-Groom, Beverley (author)
- University of Worcester
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- Barber, Adam (author)
- Met Office
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- de Vere, Natasha (author)
- Aberystwyth University,National Botanic Garden of Wales
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- Economou, Theo (author)
- University of Exeter,Met Office
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- Hegarty, Matthew (author)
- Aberystwyth University
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- Hanlon, Helen M (author)
- Met Office
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- Jones, Laura (author)
- National Botanic Garden of Wales
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- Kurganskiy, Alexander (author)
- University of Exeter
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- Petch, Geoffrey M (author)
- University of Worcester
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- Potter, Caitlin (author)
- Aberystwyth University
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- Rafiq, Abdullah M (author)
- Bangor University
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- Warner, Amena (author)
- Allergy UK
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- Wheeler, Benedict (author)
- University of Exeter
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- Osborne, Nicholas J (author)
- University of Exeter
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- Creer, Simon (author)
- Bangor University
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(creator_code:org_t)
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- Elsevier BV, 2021
- 2021
- English 9 s.
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In: Current Biology. - : Elsevier BV. - 1879-0445 .- 0960-9822. ; 31:9, s. 4-2003
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Abstract
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- Grass (Poaceae) pollen is the most important outdoor aeroallergen,1 exacerbating a range of respiratory conditions, including allergic asthma and rhinitis ("hay fever").2-5 Understanding the relationships between respiratory diseases and airborne grass pollen with a view to improving forecasting has broad public health and socioeconomic relevance. It is estimated that there are over 400 million people with allergic rhinitis6 and over 300 million with asthma, globally,7 often comorbidly.8 In the UK, allergic asthma has an annual cost of around US$ 2.8 billion (2017).9 The relative contributions of the >11,000 (worldwide) grass species (C. Osborne et al., 2011, Botany Conference, abstract) to respiratory health have been unresolved,10 as grass pollen cannot be readily discriminated using standard microscopy.11 Instead, here we used novel environmental DNA (eDNA) sampling and qPCR12-15 to measure the relative abundances of airborne pollen from common grass species during two grass pollen seasons (2016 and 2017) across the UK. We quantitatively demonstrate discrete spatiotemporal patterns in airborne grass pollen assemblages. Using a series of generalized additive models (GAMs), we explore the relationship between the incidences of airborne pollen and severe asthma exacerbations (sub-weekly) and prescribing rates of drugs for respiratory allergies (monthly). Our results indicate that a subset of grass species may have disproportionate influence on these population-scale respiratory health responses during peak grass pollen concentrations. The work demonstrates the need for sensitive and detailed biomonitoring of harmful aeroallergens in order to investigate and mitigate their impacts on human health.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Rowney, Francis ...
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Brennan, Georgin ...
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Skjøth, Carsten ...
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Griffith, Gareth ...
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McInnes, Rachel ...
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Clewlow, Yolanda
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show more...
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Adams-Groom, Bev ...
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Barber, Adam
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de Vere, Natasha
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Economou, Theo
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Hegarty, Matthew
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Hanlon, Helen M
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Jones, Laura
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Kurganskiy, Alex ...
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Petch, Geoffrey ...
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Potter, Caitlin
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Rafiq, Abdullah ...
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Warner, Amena
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Wheeler, Benedic ...
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Osborne, Nichola ...
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Creer, Simon
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
- Articles in the publication
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Current Biology
- By the university
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Lund University