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Analysis of Attaine...
Analysis of Attained Height and Diabetes Among 554,122 Adults Across 25 Low- and Middle-Income Countries
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- Teufel, Felix (author)
- Heidelberg University
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- Geldsetzer, Pascal (author)
- Heidelberg University,Stanford University
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- Manne-Goehler, Jennifer (author)
- Brigham and Women's Hospital / Harvard Medical School,Massachusetts General Hospital
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- Karlsson, Omar (author)
- Lund University,Lunds universitet,Centrum för ekonomisk demografi,Ekonomihögskolan,Centre for Economic Demography,Lund University School of Economics and Management, LUSEM,Harvard T.H. Chan School of Public Health
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- Koncz, Viola (author)
- University Hospital Heidelberg,Ludwig-Maximilian University of Munich
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- Deckert, Andreas (author)
- Heidelberg University
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- Theilmann, Michaela (author)
- Heidelberg University
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- Marcus, Maja-Emilia (author)
- University of Göttingen
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- Ebert, Cara (author)
- Rheinisch-Westfälisches Institut für Wirtschaftsforschung
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- Seiglie, Jacqueline A (author)
- Harvard Medical School
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- Agoudavi, Kokou (author)
- Togo Ministry of Health
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- Andall-Brereton, Glennis (author)
- Caribbean Public Health Agency
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- Gathecha, Gladwell (author)
- Kenya Ministry of Health
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- Gurung, Mongal S (author)
- Bhutan Ministry of Health
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- Guwatudde, David (author)
- Makerere University
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- Houehanou, Corine (author)
- University of Abomey Calavi (UAC)
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- Hwalla, Nahla (author)
- American University of Beirut
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- Kagaruki, Gibson B (author)
- National Institute for Medical Research, Tanzania.
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- Karki, Khem B (author)
- Nepal Health Research Council
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- Labadarios, Demetre (author)
- Stellenbosch University
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- Martins, Joao S (author)
- National University of East Timor
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- Msaidie, Mohamed (author)
- Ministry of Health, Solidarity, Social Cohesion and Gender, Union of Comoros
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- Norov, Bolormaa (author)
- National Center for Public Health, Mongolia
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- Sibai, Abla M (author)
- American University of Beirut
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- Sturua, Lela (author)
- National Center for Disease Control and Public Health of Georgia
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- Tsabedze, Lindiwe (author)
- Eswatini Ministry of Health
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- Wesseh, Chea S (author)
- Liberia Ministry of Health
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- Davies, Justine (author)
- University of Birmingham
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- Atun, Rifat (author)
- Harvard Medical School
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- Vollmer, Sebastian (author)
- University of Göttingen
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- Subramanian, S V (author)
- Harvard T.H. Chan School of Public Health
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- Bärnighausen, Till (author)
- Africa Health Research Institute, Somkhele, South Africa.
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- Jaacks, Lindsay M (author)
- Public Health Foundation of India
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- De Neve, Jan-Walter (author)
- Heidelberg University
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(creator_code:org_t)
- 2020-08-06
- 2020
- English 8 s.
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In: Diabetes Care. - : American Diabetes Association. - 1935-5548 .- 0149-5992. ; 43:10, s. 2403-2410
- Related links:
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http://dx.doi.org/10...
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https://care.diabete...
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https://lup.lub.lu.s...
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https://doi.org/10.2...
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Abstract
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- OBJECTIVE: The prevalence of type 2 diabetes is rising rapidly in low-income and middle-income countries (LMICs), but the factors driving this rapid increase are not well understood. Adult height, in particular shorter height, has been suggested to contribute to the pathophysiology and epidemiology of diabetes and may inform how adverse environmental conditions in early life affect diabetes risk. We therefore systematically analyzed the association of adult height and diabetes across LMICs, where such conditions are prominent.RESEARCH DESIGN AND METHODS: We pooled individual-level data from nationally representative surveys in LMICs that included anthropometric measurements and diabetes biomarkers. We calculated odds ratios (ORs) for the relationship between attained adult height and diabetes using multilevel mixed-effects logistic regression models. We estimated ORs for the pooled sample, major world regions, and individual countries, in addition to stratifying all analyses by sex. We examined heterogeneity by individual-level characteristics.RESULTS: Our sample included 554,122 individuals across 25 population-based surveys. Average height was 161.7 cm (95% CI 161.2-162.3), and the crude prevalence of diabetes was 7.5% (95% CI 6.9-8.2). We found no relationship between adult height and diabetes across LMICs globally or in most world regions. When stratifying our sample by country and sex, we found an inverse association between adult height and diabetes in 5% of analyses (2 out of 50). Results were robust to alternative model specifications.CONCLUSIONS: Adult height is not associated with diabetes across LMICs. Environmental factors in early life reflected in attained adult height likely differ from those predisposing individuals for diabetes.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Teufel, Felix
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Geldsetzer, Pasc ...
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Manne-Goehler, J ...
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Karlsson, Omar
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Koncz, Viola
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Deckert, Andreas
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show more...
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Theilmann, Micha ...
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Marcus, Maja-Emi ...
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Ebert, Cara
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Seiglie, Jacquel ...
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Agoudavi, Kokou
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Andall-Brereton, ...
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Gathecha, Gladwe ...
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Gurung, Mongal S
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Guwatudde, David
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Houehanou, Corin ...
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Hwalla, Nahla
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Kagaruki, Gibson ...
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Karki, Khem B
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Labadarios, Deme ...
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Martins, Joao S
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Msaidie, Mohamed
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Norov, Bolormaa
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Sibai, Abla M
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Sturua, Lela
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Tsabedze, Lindiw ...
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Wesseh, Chea S
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Davies, Justine
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Atun, Rifat
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Vollmer, Sebasti ...
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Subramanian, S V
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Bärnighausen, Ti ...
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Jaacks, Lindsay ...
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De Neve, Jan-Wal ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Health Care Serv ...
- Articles in the publication
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Diabetes Care
- By the university
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Lund University