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Redox Chemistry of ...
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Bulow, LeifLund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
(författare)
Redox Chemistry of Hemoglobin-Associated Disorders
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
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Mary Ann Liebert Inc,2017
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3 s.
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LIBRIS-ID:oai:lup.lub.lu.se:662878c1-b3a4-4fb6-8966-e795586af845
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https://lup.lub.lu.se/record/662878c1-b3a4-4fb6-8966-e795586af845URI
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https://doi.org/10.1089/ars.2016.6948DOI
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Språk:engelska
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Sammanfattning på:engelska
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This Forum addresses oxidative reactions of hemoglobin (Hb) and explores the underlying mechanisms of some of these reactions that contribute to the pathophysiology associated with hemolytic anemia and Hb-based oxygen therapeutics. A special focus of this Forum is on the understanding of naturally occurring mutations in human Hb and how these mutations were influenced overtime by variety of oxidative stresses. What emerges from these contributions is that some hemoglobinopathies involve mutant Hb that resists oxidative challenges, whereas the majority often result in circulatory disorder. The contributors provide in-depth and comprehensive overviews on selected key mechanisms underlying Hb oxidative reactions in health and in disease states and how this knowledge may help in the design of countermeasures against these oxidative and toxicological pathways. Antioxid. Redox Signal. 26, 745-747.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Alayash, Abdu I.FDA Center for Biologics Evaluation and Research
(författare)
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Tillämpad biokemiCentrum för tillämpade biovetenskaper
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Antioxidants and Redox Signaling: Mary Ann Liebert Inc26:14, s. 745-7471523-08641557-7716
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