Small bowel capsule endoscopy in obscure gastrointestinal bleeding : A matched cohort comparison of patients with normal vs surgically altered gastric anatomy

Background: Little is known about small bowel capsule endoscopy (SBCE) outcomes in patients with surgically altered anatomy. Aims: To assess the feasibility and diagnostic yield of orally ingested SBCE to investigate obscure gastrointestinal bleeding (OGIB) in patients with surgically altered gastric anatomy, compared to native gastric anatomy. Methods: 207 patients with OGIB were selected from an open, multicenter, retrospective cohort (SAGA study) and match-paired according to age, gender and bleeding type (overt/occult) to 207 control patients from a randomized controlled trial (PREPINTEST). Primary outcomes were the diagnostic yield (P1 or P2 findings), completion rate, adverse events rate, and small bowel transit time (SBTT). Results: The diagnostic yield was not statistically different between groups (44.9% in SAGA vs 42.5% in control patients). Inflammatory/ulcerated lesions were significantly more frequent in patients with SAGA (43.0% vs 29.3%). The median SBTT was significantly longer in the SAGA group than in control patients (283 vs 206 minutes), with a significantly lower completion rate (82.6% vs 89.9%); Adverse events were scarce (0.5% vs 0.0%). Conclusion: Patients with surgically altered gastric anatomy should benefit from SBCE investigation for OGIB as much as non-operated patients.

Rahmi, GabrielHôpital Européen Georges-Pompidou (författare)
Riccioni, Maria ElenaPoliclinico Universitario Agostino Gemelli (författare)
Vanbiervliet, GeoffroyHôpital de l’Archet / CHU de Nice (författare)
Johansson, Gabriele WurmLund University,Lunds universitet,Gastroenterologi,Forskargrupper vid Lunds universitet,Gastroenterology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-giw (författare)
Leandri, ChloéCochin Hospital (författare)
Baltes, Peter (författare)
Duburque, Clotilde (författare)
Cholet, FranckUniversity Hospital of Brest (författare)
Koulaouzidis, AnastasiosOdense University Hospital,Pomeranian Medical University(Swepub:lu)med-aku (författare)
Quénéhervé, LucilleUniversity Hospital of Brest (författare)
Paris-Sorbonne UniversityHôpital Européen Georges-Pompidou (creator_code:org_t)
I-CARE group and the PREPINTEST study group

Ingår i:Clinics and Research in Hepatology and Gastroenterology: Elsevier BV46:72210-7401

Av författaren/redakt...: Dray, Xavier; Rahmi, Gabriel; Riccioni, Maria ...; Vanbiervliet, Ge ...; Johansson, Gabri ...; Leandri, Chloé; visa fler...; Baltes, Peter; Duburque, Clotil ...; Cholet, Franck; Koulaouzidis, An ...; Quénéhervé, Luci ...; visa färre...

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