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International myelo...
International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100)
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Giralt, S. (author)
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Stadtmauer, E. A. (author)
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Harousseau, J. L. (author)
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Palumbo, A. (author)
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Bensinger, W. (author)
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Comenzo, R. L. (author)
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Kumar, S. (author)
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Munshi, N. C. (author)
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Dispenzieri, A. (author)
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Kyle, R. (author)
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Merlini, G. (author)
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San Miguel, J. (author)
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Ludwig, H. (author)
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Hajek, R. (author)
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Jagannath, S. (author)
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Blade, J. (author)
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Lonial, S. (author)
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Dimopoulos, M. A. (author)
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Einsele, H. (author)
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Barlogie, B. (author)
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Anderson, K. C. (author)
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Gertz, M. (author)
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Attal, M. (author)
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Tosi, P. (author)
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Sonneveld, P. (author)
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Boccadoro, M. (author)
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Morgan, G. (author)
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Sezer, O. (author)
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Mateos, M. V. (author)
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Cavo, M. (author)
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Joshua, D. (author)
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- Turesson, Ingemar (author)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
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Chen, W. (author)
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Shimizu, K. (author)
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Powles, R. (author)
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Richardson, P. G. (author)
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Niesvizky, R. (author)
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Rajkumar, S. V. (author)
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Durie, B. G. M. (author)
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(creator_code:org_t)
- 2009-06-25
- 2009
- English.
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In: Leukemia. - : Springer Science and Business Media LLC. - 1476-5551 .- 0887-6924. ; 23:10, s. 1904-1912
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http://dx.doi.org/10...
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https://www.nature.c...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- Multiple myeloma is the most common indication for high-dose chemotherapy with autologous stem cell support (ASCT) in North America today. Stem cell procurement for ASCT has most commonly been performed with stem cell mobilization using colony-stimulating factors with or without prior chemotherapy. The target CD34+ cell dose to be collected as well as the number of apheresis performed varies throughout the country, but a minimum of 2 million CD34+ cells/kg has been traditionally used for the support of one cycle of high-dose therapy. With the advent of plerixafor (AMD3100) (a novel stem cell mobilization agent), it is pertinent to review the current status of stem cell mobilization for myeloma as well as the role of autologous stem cell transplantation in this disease. On June 1, 2008, a panel of experts was convened by the International Myeloma Foundation to address issues regarding stem cell mobilization and autologous transplantation in myeloma in the context of new therapies. The panel was asked to discuss a variety of issues regarding stem cell collection and transplantation in myeloma especially with the arrival of plerixafor. Herein, is a summary of their deliberations and conclusions. Leukemia (2009) 23, 1904-1912; doi: 10.1038/leu.2009.127; published online 25 June 2009
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- high-dose therapy
- stem cell collection
- myeloma
- plerixafor
- IMWG
- guidelines
Publication and Content Type
- art (subject category)
- ref (subject category)
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Leukemia
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- By the author/editor
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Giralt, S.
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Stadtmauer, E. A ...
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Harousseau, J. L ...
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Palumbo, A.
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Bensinger, W.
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Comenzo, R. L.
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show more...
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Kumar, S.
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Munshi, N. C.
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Dispenzieri, A.
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Kyle, R.
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Merlini, G.
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San Miguel, J.
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Ludwig, H.
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Hajek, R.
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Jagannath, S.
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Blade, J.
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Lonial, S.
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Dimopoulos, M. A ...
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Einsele, H.
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Barlogie, B.
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Anderson, K. C.
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Gertz, M.
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Attal, M.
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Tosi, P.
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Sonneveld, P.
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Boccadoro, M.
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Morgan, G.
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Sezer, O.
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Mateos, M. V.
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Cavo, M.
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Joshua, D.
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Turesson, Ingema ...
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Chen, W.
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Shimizu, K.
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Powles, R.
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Richardson, P. G ...
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Niesvizky, R.
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Rajkumar, S. V.
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Durie, B. G. M.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Leukemia
- By the university
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Lund University
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Karolinska Institutet