Antimicrobial activity of metabolites from mycelial cultures of Chilean Basidiomycetes

We reported seven compounds isolated from mycelial cultures of Chilean Basidiomycetes. The compound structures were elucidated by spectroscopic methods. Two polyacetylenes were isolated from Gymnopilus spectabilis: hepta-4,6-diyn-3-ol (1) and 7-chloro-hepta-4,6-diyn-3 ol (2). We isolated the aromatic compounds p-anisaldehyde (3) and 3-chloro-p-anisaldehyde (4) from Hypholoma capnoides. H. fasciculare produced the compounds (3), (4), 3,5-dichloro-4-metoxi-benzyl alcohol (5) and the sesquiterpen naematolon (6). Finally, H. sublateritium produced (5) and another sesquiterpen, marasmal (7). The compounds (1), (2), (5), and (7) showed biological activity against the tested model microorganism.

Becerra, Jose (author)
Palfner, Gotz (author)
Silva, Mario (author)
Alarcon, Julio (author)
Anke, Timm (author)
Sterner, OlovLund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH(Swepub:lu)ok2-ost (author)
Centrum för analys och syntesKemiska institutionen (creator_code:org_t)

By the author/editor: Aqueveque, Pedro; Becerra, Jose; Palfner, Gotz; Silva, Mario; Alarcon, Julio; Anke, Timm; show more...; Sterner, Olov; show less...

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NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...; and Organic Chemistr ...

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