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- Laučytė-Cibulskienė, AgnėLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital (author)
Updated Pathways in Cardiorenal Continuum after Kidney Transplantation
- Article/chapterEnglish2022
Publisher, publication year, extent ...
- 2022-05-02
- MDPI AG,2022
- 13 s.
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:6e0c76b8-14c8-4a9a-b7d9-837cc50beaad
- https://lup.lub.lu.se/record/6e0c76b8-14c8-4a9a-b7d9-837cc50beaadURI
- https://doi.org/10.3390/transplantology3020017DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Cardiovascular disease (CVD) remains one of the leading causes for increased morbidity and mortality in chronic kidney disease (CKD). Kidney transplantation is the preferred treatment option for CKD G5. Improved perioperative and postoperative care, personalized immunosuppressive regimes, and refined matching procedures of kidney transplants improves cardiovascular health in the early posttransplant period. However, the long-term burden of CVD is considerable. Previously underrecognized, the role of the complement system alongside innate immunity, inflammaging, structural changes in the glomerular filtration barrier and early vascular ageing also seem to play an important role in the posttransplant management. This review provides up-to-date knowledge on these pathways that may influence the cardiovascular and renal continuum and identifies potential targets for future therapies. Arterial destiffening strategies and the applicability of sodium-glucose cotransporter 2 inhibitors and their role in cardiovascular health after kidney transplantation are also addressed.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Urologi och njurmedicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Urology and Nephrology hsv//eng
- arterial stiffness
- complement system
- cystatin C
- kidney transplant
- microbiome
- sodium-glucose cotransporter 2 inhibitors
Added entries (persons, corporate bodies, meetings, titles ...)
- Biglarnia, Ali RezaSkåne University Hospital (author)
- Wallquist, CarinLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)ca5505wa (author)
- Christensson, AndersLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)medf-ach (author)
- Internmedicin - epidemiologiForskargrupper vid Lunds universitet (creator_code:org_t)
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- In:Transplantology: MDPI AG3:2, s. 156-1682673-3943
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