Search: onr:"swepub:oai:lup.lub.lu.se:704415e5-bbd2-4fcf-9768-93cc5679a8be" >
Effects of the DICE...
-
Eikelboom, Willem S.Erasmus University Medical Center
(author)
Effects of the DICE Method to Improve Timely Recognition and Treatment of Neuropsychiatric Symptoms in Early Alzheimer's Disease at the Memory Clinic : The BEAT-IT Study
- Article/chapterEnglish2023
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:704415e5-bbd2-4fcf-9768-93cc5679a8be
-
https://lup.lub.lu.se/record/704415e5-bbd2-4fcf-9768-93cc5679a8beURI
-
https://doi.org/10.3233/JAD-230116DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
Background: Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-pharmacological interventions are scarcely implemented. Objective: To evaluate the effectiveness of the Describe, Investigate, Create, Evaluate (DICE) method™ to improve the care for NPS in AD at the memory clinic. Methods: We enrolled sixty community-dwelling people with mild cognitive impairment or AD dementia and NPS across six Dutch memory clinics with their caregivers. The first wave underwent care as usual (n = 36) and the second wave underwent the DICE method (n = 24). Outcomes were quality of life (QoL), caregiver burden, NPS severity, NPS-related distress, competence managing NPS, and psychotropic drug use. Reliable change index was calculated to identify responders to the intervention. A cost-effectiveness analysis was performed and semi-structured interviews with a subsample of the intervention group (n = 12). Results: The DICE method did not improve any outcomes over time compared to care as usual. Half of the participants of the intervention group (52%) were identified as responders and showed more NPS and NPS-related distress at baseline compared to non-responders. Interviews revealed substantial heterogeneity among participants regarding NPS-related distress, caregiver burden, and availability of social support. The intervention did not lead to significant gains in quality-adjusted life years and well-being years nor clear savings in health care and societal costs. Conclusion: The DICE method showed no benefits at group-level, but individuals with high levels of NPS and NPS-related distress may benefit from this intervention.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Van Den Berg, EstherErasmus University Medical Center
(author)
-
Coesmans, MichielErasmus University Medical Center
(author)
-
Goudzwaard, Jeannette A.Erasmus University Medical Center
(author)
-
Koopmanschap, MarcErasmus University Rotterdam
(author)
-
Lazaar, NajouaErasmus University Medical Center
(author)
-
Van Bruchem-Visser, Rozemarijn L.Erasmus University Medical Center
(author)
-
Driesen, Jan J.M.Franciscus Gasthuis & Vlietland
(author)
-
Den Heijer, TomFranciscus Gasthuis & Vlietland
(author)
-
Hoogers, SusanneSpijkenisse Medical Center
(author)
-
De Jong, Frank JanErasmus University Medical Center
(author)
-
Mattace-Raso, Francesco U. S.Erasmus University Medical Center
(author)
-
Thomeer, Elsbeth C.Maasstad Ziekenhuis
(author)
-
Vrenken, SuzanneSpijkenisse Medical Center
(author)
-
Vroegindeweij, Lilian J.H.M.Van Weel-Bethesda Hospital
(author)
-
Zuidema, Sytse U.University Medical Center Groningen
(author)
-
Singleton, Ellen H.Amsterdam UMC - Vrije Universiteit Amsterdam
(author)
-
Van Swieten, John C.Erasmus University Medical Center
(author)
-
Ossenkoppele, RikLund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Clinical Memory Research,Lund University Research Groups,LU Profile Area: Proactive Ageing,Lund University Profile areas,Amsterdam UMC - Vrije Universiteit Amsterdam(Swepub:lu)ri1513os
(author)
-
Papma, Janne M.Erasmus University Medical Center
(author)
-
Erasmus University Medical CenterErasmus University Rotterdam
(creator_code:org_t)
Related titles
-
In:Journal of Alzheimer's Disease93:4, s. 1407-14231387-2877
Internet link
Find in a library
To the university's database
- By the author/editor
-
Eikelboom, Wille ...
-
Van Den Berg, Es ...
-
Coesmans, Michie ...
-
Goudzwaard, Jean ...
-
Koopmanschap, Ma ...
-
Lazaar, Najoua
-
show more...
-
Van Bruchem-Viss ...
-
Driesen, Jan J.M ...
-
Den Heijer, Tom
-
Hoogers, Susanne
-
De Jong, Frank J ...
-
Mattace-Raso, Fr ...
-
Thomeer, Elsbeth ...
-
Vrenken, Suzanne
-
Vroegindeweij, L ...
-
Zuidema, Sytse U ...
-
Singleton, Ellen ...
-
Van Swieten, Joh ...
-
Ossenkoppele, Ri ...
-
Papma, Janne M.
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Geriatrics
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Other Medical an ...
-
and Gerontology spec ...
- Articles in the publication
-
Journal of Alzhe ...
- By the university
-
Lund University