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Genome-wide associa...
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
- Article/chapterEnglish2012
Publisher, publication year, extent ...
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2012-09-23
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Springer Science and Business Media LLC,2012
Numbers
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LIBRIS-ID:oai:lup.lub.lu.se:72773106-a12e-4cbb-8a5e-550403775f69
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https://lup.lub.lu.se/record/3283699URI
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https://doi.org/10.1038/ng.2417DOI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 x 10(-13); odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 x 10(-15); OR = 1.50).
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Lemnrau, Alina
(author)
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Cooke, Rosie
(author)
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Fletcher, Olivia
(author)
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Tomczyk, Katarzyna
(author)
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Jones, Michael
(author)
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Johnson, Nichola
(author)
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Lord, Christopher J.
(author)
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Mitsopoulos, Costas
(author)
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Zvelebil, Marketa
(author)
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McDade, Simon S.
(author)
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Buck, Gemma
(author)
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Blancher, Christine
(author)
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Trainer, Alison H.
(author)
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James, Paul A.
(author)
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Bojesen, Stig E.
(author)
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Bokmand, Susanne
(author)
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Nevanlinna, Heli
(author)
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Mattson, Johanna
(author)
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Friedman, Eitan
(author)
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Laitman, Yael
(author)
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Palli, Domenico
(author)
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Masala, Giovanna
(author)
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Zanna, Ines
(author)
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Ottini, Laura
(author)
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Giannini, Giuseppe
(author)
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Hollestelle, Antoinette
(author)
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van den Ouweland, Ans M. W.
(author)
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Novakovic, Srdjan
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Krajc, Mateja
(author)
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Gago-Dominguez, Manuela
(author)
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Castelao, Jose Esteban
(author)
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Olsson, HåkanLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)onk-hol
(author)
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Hedenfalk, IngridLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bröst- och ovarialcancer,Forskargrupper vid Lunds universitet,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Breast and Ovarian Cancer Genomics,Lund University Research Groups(Swepub:lu)onk-ifa
(author)
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Easton, Douglas F.
(author)
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Pharoah, Paul D. P.
(author)
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Dunning, Alison M.
(author)
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Bishop, D. Timothy
(author)
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Neuhausen, Susan L.
(author)
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Steele, Linda
(author)
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Houlston, Richard S.
(author)
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Garcia-Closas, Montserrat
(author)
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Ashworth, Alan
(author)
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Swerdlow, Anthony J.
(author)
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Bröstcancer-genetikSektion I
(creator_code:org_t)
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In:Nature Genetics: Springer Science and Business Media LLC44:11, s. 1182-11841546-17181061-4036
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Orr, Nick
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Lemnrau, Alina
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Cooke, Rosie
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Fletcher, Olivia
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Tomczyk, Katarzy ...
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Jones, Michael
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Johnson, Nichola
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Lord, Christophe ...
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Mitsopoulos, Cos ...
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Zvelebil, Market ...
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McDade, Simon S.
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Buck, Gemma
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Blancher, Christ ...
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Trainer, Alison ...
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James, Paul A.
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Bojesen, Stig E.
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Bokmand, Susanne
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Nevanlinna, Heli
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Mattson, Johanna
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Friedman, Eitan
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Laitman, Yael
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Palli, Domenico
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Masala, Giovanna
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Zanna, Ines
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Ottini, Laura
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Giannini, Giusep ...
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Hollestelle, Ant ...
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van den Ouweland ...
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Novakovic, Srdja ...
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Krajc, Mateja
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Gago-Dominguez, ...
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Castelao, Jose E ...
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Olsson, Håkan
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Hedenfalk, Ingri ...
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Easton, Douglas ...
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Pharoah, Paul D. ...
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Dunning, Alison ...
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Bishop, D. Timot ...
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Neuhausen, Susan ...
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Steele, Linda
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Houlston, Richar ...
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Garcia-Closas, M ...
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Ashworth, Alan
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Swerdlow, Anthon ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
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Nature Genetics
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Lund University